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MetabolomicsSoftware tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values

BACKGROUND: Lipidomics, the comprehensive measurement of lipids within a biological system or substrate, is an emerging field with significant potential for improving clinical diagnosis and our understanding of health and disease. While lipids diverse biological roles contribute ...

2022-05-17 | MTBLS710 | MetaboLights
Unknown"It is not the fault of the health care team - it is the way the system works": a mixed-methods quality improvement study of patients with advanced cancer and family members reveals challenges navigating a fragmented healthcare system and the administrative and financial burdens of care.
Not available
S-EPMC11552108 | biostudies-literature
ModelsAbbott2021 - Prediction of Immunotherapy Response in Melanoma through Combined Modeling of NB and Immune-Related Resistance Mechanisms
In this manuscript, the authors had hypothesized a multi-dimensional approach modeling of both tumor and immune-related molecular mechanisms would better predict immune checkpoint blockade (ICB) response than simpler mutation-focused biomarkers, such as tumor mutational burden (TMB). The authors sho...
2024-07-23 | MODEL2407210001 | BioModels
Machine Learning Model 
UnknownRandomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed.
Not available
S-EPMC5089161 | biostudies-literature
UnknownActive idiotypic vaccination versus control immunotherapy for follicular lymphoma.
Not available
S-EPMC4039868 | biostudies-literature
TranscriptomicsImmune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival.
Although remission rates for metastatic melanoma are generally very poor, some patients can survive for prolonged periods following metastasis. We used gene expression profiling, mitotic index (MI), and quantification of tumor infiltrating leukocytes (TILs) and CD3+ cells in metastatic lesions to se...
ORGANISM(S): Homo sapiens 
2009-11-30 | E-GEOD-19234 | biostudies-arrayexpress
UnknownLack of correlation between outcomes of membrane repair assay and correction of dystrophic changes in experimental therapeutic strategy in dysferlinopathy.
Not available
S-EPMC3362551 | biostudies-literature
TranscriptomicsRNA-Seq of SOX4 and HOXD3 CRISPR KO SupT1 cells against wildtype SupT1 cells during HIV-1 infection
poly-A enrichment RNASeq on RNA samples isolated from SupT1 cells with lentiviral mediated CRISPR SOX4 and HOXD3 KO against wildtype SupT1 during the time course of HIV infection (uninfected, 8, 18, 30 and 42hpi). SupT1 cells were spinofected with NLENG1-IRES G1I molecular HIV-1 clone. After RNA iso...
ORGANISM(S): Homo sapiens 
2022-11-01 | E-MTAB-8444 | biostudies-arrayexpress
UnknownObstructive Sleep Apnea: A Cluster Analysis at Time of Diagnosis.
Not available
S-EPMC4912165 | biostudies-literature
UnknownA randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therapy for metastatic triple-negative breast cancer (fRida).
Not available
S-EPMC8558154 | biostudies-literature
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