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TranscriptomicsGene expression signatures for primary tumor and tumor-derived exosomes
To determine the different gene signatures between primary tumor and tumor-derived exosomes, we have employed RNA-sequencing as a discovery platform to identify gene signatures of tumor-derived exosomes, taking the original tumors as a control. We subcutaneously inoculated C57BL/6 mice with Lewis lu...
ORGANISM(S): Mus musculus 
2016-08-10 | E-GEOD-80678 | biostudies-arrayexpress
ProteomicsMetaprotemic analysis of groundwaters from a coal tar-contaminated aquifer in South Glens Falls, NY: MW37, Gel Slice
Deciphering the in situ activities of microorganisms is essential for understanding the biogeochemical processes occurring in complex environments. Here we used environmental metaproteomics to obtain information about the identity and activity of subsurface microbial populations in coal-tar-contamin...
ORGANISM(S): prokaryotic environmental samples 
2022-02-22 | PXD001035 | Pride
In-situ gene expression  microbial ecology  metaproteomics  candidatus methylomirabilis oxyfera 
ProteomicsMetaprotemic analysis of groundwaters from a coal tar-contaminated aquifer in South Glens Falls, NY: MW37, Shotgun 2
Deciphering the in situ activities of microorganisms is essential for understanding the biogeochemical processes occurring in complex environments. Here we used environmental metaproteomics to obtain information about the identity and activity of subsurface microbial populations in coal-tar-contamin...
ORGANISM(S): prokaryotic environmental samples 
2022-02-22 | PXD001037 | Pride
In-situ gene expression  microbial ecology  metaproteomics  candidatus methylomirabilis oxyfera 
ProteomicsMetaprotemic analysis of groundwaters from a coal tar-contaminated aquifer in South Glens Falls, NY: MW37, Shotgun 1
Deciphering the in situ activities of microorganisms is essential for understanding the biogeochemical processes occurring in complex environments. Here we used environmental metaproteomics to obtain information about the identity and activity of subsurface microbial populations in coal-tar-contamin...
ORGANISM(S): prokaryotic environmental samples 
2022-02-22 | PXD001036 | Pride
In-situ gene expression  microbial ecology  metaproteomics  candidatus methylomirabilis oxyfera 
UnknownIdentifying active vascular microcalcification by (18)F-sodium fluoride positron emission tomography.
Not available
S-EPMC4506997 | biostudies-literature
TranscriptomicsDifference expression analyses before and after human fucosyltransferase gene 1 transfection into ovarian cancer clear cell line
75% ovarian epithelial tumor overexpresses Lewis y antigen, which notably strenthen such malignant biological behaviors as metastasis, drug resistance and proliferation. The key enzyme of Lewis y synthesis is human fucosyltransferase gene 1(hfut1). Through transfecting hfut1 into Lewis y low expres...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-GEOD-34396 | biostudies-arrayexpress
ProteomicsComprehensive O-GlcNAc glycoproteomics on NOTCH1 EGF repeats refined sequons for O-GlcNAcylation and uncovered unique Lewis X epitopes in mammals
The O-GlcNAc modification of Notch receptors regulates Notch ligand interactions in a manner distinct from other forms of O-glycans on epidermal growth factor-like (EGF) repeats of Notch receptors. Although many proteins, besides Notch receptors, are expected to be O-GlcNAcylated by EGF domain-speci...
ORGANISM(S): Mus Musculus (mouse) 
2022-11-03 | PXD029528 | JPOST Repository
ProteomicsComprehensive O-GlcNAc glycoproteomics on NOTCH1 EGF repeats refined sequons for O-GlcNAcylation and uncovered unique Lewis X epitopes in mammals
The O-GlcNAc modification of Notch receptors regulates Notch ligand interactions in a manner distinct from other forms of O-glycans on epidermal growth factor-like (EGF) repeats of Notch receptors. Although many proteins, besides Notch receptors, are expected to be O-GlcNAcylated by EGF domain-speci...
ORGANISM(S): Mus Musculus (mouse) 
2022-11-02 | PXD029482 | JPOST Repository
TranscriptomicsGene expression profile of preclinical arthritis and its modulation by antigen-induced tolerance
During the course of adjuvant arthritis, maximal changes in gene expression were observed at the incubation phase. A major group of genes affected was related to immune activity. Tolerance induction by mycobacterial heat-shock protein 65 (Bhsp65), the disease-related antigen, caused upregulation of ...
ORGANISM(S): Rattus norvegicus 
2011-11-16 | E-GEOD-31314 | biostudies-arrayexpress
UnknownAge-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study.
Not available
S-EPMC4729397 | biostudies-literature
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