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MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
UnknownSelectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.
Not available
S-EPMC6485480 | biostudies-literature
UnknownBaseline Psychological Traits Contribute to Lake Louise Acute Mountain Sickness Score at High Altitude.
Not available
S-EPMC8982137 | biostudies-literature
ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
UnknownReproducibility of Ocular Surface Staining in the Assessment of Sjogren Syndrome-Related Keratoconjunctivitis Sicca: Implications on Disease Classification.
Not available
S-EPMC6710016 | biostudies-literature
MetabolomicsEpithelial-Cell-Derived Phospholipase A2 Group 1B Is an Endogenous Anthelmintic
Immunity to intestinal helminth infections has been well studied, but the mechanism of helminth killing prior to expulsion remains unclear. Here we identify epithelial-cell-derived phospholipase A2 group 1B (PLA2g1B) as a host-derived endogenous anthelmintic. PLA2g1B is elevated in resistant mice an...
2018-08-13 | MTBLS523 | MetaboLights
TranscriptomicsMicroarray analyses of mouse dorsal root ganglia tissue for six different pain models
Six different mouse pain models were studied: (1) tumour-injection model for bone cancer pain; (2) partial sciatic nerve ligation (PSL) for neuropathic pain; (3) mechanical joint loading for osteoarthritis pain; (4) oxaliplatin-induced painful neuropathy for chemotherapy-induced pain; (5) hyperalges...
ORGANISM(S): Mus musculus 
2018-06-11 | E-MTAB-6864 | biostudies-arrayexpress
UnknownA unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide.
Not available
S-EPMC4140462 | biostudies-literature
UnknownHuman Rhinovirus Diversity and Evolution: How Strange the Change from Major to Minor.
Not available
S-EPMC5355621 | biostudies-literature
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