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ProteomicsLGALS3BP modulates local gyrification in the human brain
Basal radial glial cells (bRGs) are neural progenitors enriched in primates and humans and were proposed to contribute to the expansion of neurons during cortical development in gyrencephalic species. Shortly after their generation, bRGs delaminate towards the outer subventricular zone, where they d...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-10-26 | PXD015878 | Pride
Delamination Human brain development Evolution Lgals3bp Human cortical gyrification Basal radial glial cells Cerebral organoids Extracellular matrix Developmental disorders 
GenomicsThe extracellular function of LGALS3BP in neural progenitors during brain development
The extracellular function of LGALS3BP in neural progenitors during brain development
PRJEB44886 | ENA
UnknownSecreted LGALS3BP facilitates distant metastasis of breast cancer.
Not available
S-EPMC11715970 | biostudies-literature
TranscriptomicsThe extracellular function of LGALS3BP in neural progenitors during brain development
This study demonstrates cellular and molecular mechanisms regulating the generation and function of basal radial glia (bRG), a neural stem cell population that was shown to be enriched in the developing human brain and was involved in the formation of cortical expansion. Here, we studied the role of...
ORGANISM(S): Homo sapiens 
2021-05-12 | E-MTAB-10485 | biostudies-arrayexpress
GenomicsGalectin 3-binding protein (Lgals3bp) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis [ATAC-seq]
Background: Increased Galectin 3-binding protein (Lgals3bp) serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma (HCC). Considering the crucial role of transforming growth factor-β1 (TGF-β1) in the emergence of these diseases, the present study t...
ORGANISM(S): Mus musculus 
2024-07-06 | GSE271354 | GEO
TranscriptomicsGalectin 3-binding protein (Lgals3bp) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis [RNA-seq]
Background: Increased Galectin 3-binding protein (Lgals3bp) serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma (HCC). Considering the crucial role of transforming growth factor-β1 (TGF-β1) in the emergence of these diseases, the present study t...
ORGANISM(S): Mus musculus 
2024-07-06 | GSE271352 | GEO
TranscriptomicsGalectin 3-binding protein (Lgals3bp) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis [PH RNA-seq]
Background: Increased Galectin 3-binding protein (Lgals3bp) serum levels have been used to assess hepatic fibrosis stages and the severity of hepatocellular carcinoma (HCC). Considering the crucial role of transforming growth factor-β1 (TGF-β1) in the emergence of these diseases, the present study t...
ORGANISM(S): Mus musculus 
2024-07-06 | GSE271355 | GEO
GenomicsGalectin 3-binding protein (Lgals3bp) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis [RNA-seq]
Galectin 3-binding protein (Lgals3bp) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis [RNA-seq]
PRJNA1130972 | ENA
GenomicsGalectin 3-binding protein (Lgals3bp) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis [ATAC-seq]
Galectin 3-binding protein (Lgals3bp) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis [ATAC-seq]
PRJNA1130978 | ENA
UnknownLGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia.
Not available
S-EPMC9344220 | biostudies-literature
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