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TranscriptomicsLhx1 is required for specification of renal progenitor cell field
The goal of this study is to investigate the molecular mechanism of lhx1 on regulation of pronephros formation during the early embryonic development. In the vertebrate embryo the kidney is derived from the intermediate mesoderm. The LIM-class homeobox transcription factor lhx1 is expressed early in...
ORGANISM(S): Xenopus laevis 
2010-09-29 | E-GEOD-24392 | biostudies-arrayexpress
TranscriptomicsRNAseq in whole freshwater planarians, Schmidtea mediterranea, following RNAi of the transcription factors lhx1/5-1 and pitx.
Freshwater planarians can be used as a model to investigate neuronal function and maintenance in adults in vivo. We knocked down expression for 2 transcription factors, then sequenced resulting animals to examine transcriptional changes that may have occurred. There are 3 triplicated conditions: c...
ORGANISM(S): Schmidtea mediterranea 
2013-05-31 | E-GEOD-47348 | biostudies-arrayexpress
ProteomicsXenopus A6 cells nanoLC-MS/MS - The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development
The transcriptional events driving specification of the kidney have been well characterized. However, it remains undetermined how initial kidney field size is established, patterned, and proportioned. Lhx1 is a transcription factor expressed in the kidney anlage and is required for specification of ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2019-11-11 | PXD006926 | Pride
Xenopus laevie A6 Nanolc-ms/ms Kidney epithelial cells 
UnknownLong non-coding RNA LHX1-DT regulates cardiomyocyte differentiation through H2A.Z-mediated LHX1 transcriptional activation.
Not available
S-EPMC10628816 | biostudies-literature
GenomicsThe LHX1 Gene Regulatory Network Represses Pluripotency to Specify the Embryonic Head
The LHX1 Gene Regulatory Network Represses Pluripotency to Specify the Embryonic Head
PRJNA1327345 | ENA
GenomicsA gene regulatory network driven by LIM homeobox 1 (LHX1) for embryonic head development (Microarray)
A gene regulatory network driven by LIM homeobox 1 (LHX1) for embryonic head development (Microarray)
PRJNA483125 | ENA
UnknownLhx1 is required for specification of the renal progenitor cell field.
Not available
S-EPMC3078140 | biostudies-literature
GenomicsMolecular function of Lhx1 in early mouse development (ChIP-Seq)
ChIP-seq using anti-Lhx1 antibody to map genomic binding of Lhx1 in stably transfected P19 mouse embryonic carcinoma cells
ORGANISM(S): Mus musculus 
2015-10-19 | GSE70957 | GEO
TranscriptomicsLhx1 is required for specification of renal progenitor cell field
The goal of this study is to investigate the molecular mechanism of lhx1 on regulation of pronephros formation during the early embryonic development. In the vertebrate embryo the kidney is derived from the intermediate mesoderm. The LIM-class homeobox transcription factor lhx1 is expressed early in...
ORGANISM(S): Xenopus laevis 
2010-09-29 | GSE24392 | GEO
GenomicsA gene regulatory network driven by LIM homeobox 1 (LHX1) for embryonic head development (RNA-seq)
A gene regulatory network driven by LIM homeobox 1 (LHX1) for embryonic head development (RNA-seq)
PRJNA483120 | ENA
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