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TranscriptomicsRegulation of hTERT by BCR-ABL at multiple levels in K562 cells
To investigate the mechanism of telomerase regulation in BCR-ABL positive cells due to its clinical value, we studied the catalytic component of telomerase, TERT. Our results suggest that BCR-ABL plays an important role in regulating hTERT in K562 (BCR-ABL positive human leukemia) cells. When Gleeve...
ORGANISM(S): Homo sapiens 
2011-12-15 | E-GEOD-26821 | biostudies-arrayexpress
TranscriptomicsTranscriptome of MEFs with BMP2 and DNA damage reagents
The tightly controlled BMP-Smad1 pathway is essential for embryonic development and postnatal tissue homeostasis. Dysfunction of BMP-Smad1 signaling also leads to tumor development such as juvenile polyposis and Cowden syndromes and various tumors in mouse models, with unknown pathological mechanis...
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-36843 | biostudies-arrayexpress
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
TranscriptomicsBulk RNA sequencing of three normal human pediatric kidney tissue samples
Processed count table RNA sequencing data of kidney tissue.
ORGANISM(S): Homo sapiens 
2026-09-11 | E-MTAB-17119 | biostudies-arrayexpress
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