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TranscriptomicsCharacterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation
The fetal and adult globin genes in the human b-globin cluster on chromosome 11 are sequentially expressed to achieve normal hemoglobin switching during human development. The pharmacological induction of fetal g-globin (HBG) to replace abnormal adult sickle bS-globin is a successful strategy to tre...
ORGANISM(S): Homo sapiens 
2012-01-14 | E-GEOD-35102 | biostudies-arrayexpress
TranscriptomicsCharacterization of Transcription Factor Networks Involved in Umbilical Cord Blood CD34+ Stem Cells-Derived Erythropoiesis
The characteristics of global gene expression patterns during umbilical cord blood (UCB)-CD34+ stem cell-derived erythropoiesis are not clearly elucidated. In this study, UCB-stem cells were grown in liquid culture as a model for this process. We observed a high proliferative capacity of UCB-stem ce...
ORGANISM(S): Homo sapiens 
2013-08-02 | E-GEOD-49438 | biostudies-arrayexpress
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