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MetabolomicsAMPK activation orchestrated replicative senescence of periodontal ligament stem cells via regulating metabolomics

BACKGROUND: Periodontal ligament mesenchymal stem cells (PDLSCs) are a promising cell resource for cell-based regenerative medicine in dentistry. PDLSCs inevitably acquire a senescent phenotype after prolonged in vitro expansion, and the key regulators of cells during replicative...

2022-11-15 | MTBLS4568 | MetaboLights
UnknownReactive oxygen species in the rhizosphere orchestrate the recruitment of beneficial bacteria
Not available
S-SCDT-10_1038-S44318-025-00685-W | biostudies-other
UnknownHuman Disturbance Increases Health Risks to Golden Snub-Nosed Monkeys and the Transfer Risk of Pathogenic Antibiotic-Resistant Bacteria from Golden Snub-Nosed Monkeys to Humans.
Not available
S-EPMC10572025 | biostudies-literature
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of effect of knockdown of GATA2 on AR binding sites
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare AR binding activity in LNCaP cells with and without knockdown of GATA2. Methods: LNCaP cells between passage number 32-34 were used for assay. Cells are tr...
ORGANISM(S): Homo sapiens 
2014-01-21 | E-GEOD-52725 | biostudies-arrayexpress
TranscriptomicsMiR-27a-3p in peripheral blood mononuclear cells as a potential marker for pancreatic cancer screening
Background & Aims: MicroRNAs have been shown to offer great potential in the diagnosis of cancer. We aimed to identify microRNAs in peripheral blood mononuclear cells (PBMCs) for diagnosing pancreatic cancer (PC). Methods: PBMCs microRNA expression was investigated in three independent cohorts inclu...
ORGANISM(S): Homo sapiens 
2012-05-03 | E-GEOD-37710 | biostudies-arrayexpress
TranscriptomicsA transcriptomic analysis of super-hybrid rice LYP9 and its parental lines
Using a whole-genome oligonucleotide microarray designed based on known and predicted indica rice genes, we investigated transcriptome profiles in developing leaves and panicles of super hybrid rice LYP9 and its parental cultivar 93-11 and PA64s. We detected 22,266 expressed genes out of 36,926 tota...
ORGANISM(S): Oryza sativa 
2009-04-22 | E-GEOD-14729 | biostudies-arrayexpress
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