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ProteomicsReceptor Tyrosine Kinase Inhibitors Block proliferation of coronavirus mainly through p38 mitogen-activated protein kinase pathways
Emerging coronaviruses (CoVs) primarily cause severe gastroenteric or respiratory diseases in humans and animals, for which no approved therapeutics are available so far. Here A9, a receptor tyrosine kinase inhibitors (RTKIs) of the tyrphostin class was identified as a robust inhibitor of TGEV (Tran...
ORGANISM(S): Sus scrofa (Pig) 
2020-05-26 | PXD010685 | Pride
Transmissible gastroenteritis virus Lc–ms/ms analysis. Rtkis Emerging coronaviruses 
ProteomicsLabel-free proteomic analysis of apoptotic, necrotic and necroptotic DAMPs from HNSCC cells
Necroptosis is a newly discovered form of programmed cell death (PCD) showing necrotic features, including membrane permeabilization and the release of damage-associated molecular patterns (DAMPs). Studies have revealed both its tumorigenic role and therapeutic potential in various cancers, yet its ...
ORGANISM(S): Homo Sapiens 
2022-07-16 | PXD035379 |
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