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MetabolomicsResolving coral photoacclimation dynamics through coupled photophysiological and metabolomic profiling
Corals continuously adjust to short term variation in light availability on shallow reefs. Long-term light alterations can also occur due to natural and anthropogenic stressors, as well as management interventions such as coral transplantation. Although short term photophysiological responses are re...
2019-04-11 | MTBLS768 | MetaboLights
MetabolomicsBased on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
TranscriptomicsENCODE: PolyA+ RNA from retinoic acid stimulated HL-60 cells at 4 time points (NCBIv35)
PolyA+ RNA from retinoic acid stimulated HL-60 cells at 0, 2, 8, or 32 hours using Affymetrix ENCODE tiling chip with NCBI build 35 annotation. PolyA+ RNA from retinoic acid stimulated HL-60 cells at 0, 2, 8, or 32 hours.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-3662 | biostudies-arrayexpress
TranscriptomicsUnbiased miRNA screening analysis on myo-sEVs derived from Nor or HG/HL
The current study aims were to determine the differential expression of Myo-sEVs derived from normal or HG/HL.Mouse primary myocardial cells were isolated and cultured in normal and HG/HL culture medium. Myo-sEVs were separated by ultracentrifugation.Differential myo-sEVs-miRNA expression obtained ...
ORGANISM(S): Mus musculus 
2024-02-07 | E-MTAB-13736 | biostudies-arrayexpress
UnknownA perilipin gene from Clonostachys rosea f. Catenulata HL-1-1 is related to sclerotial parasitism.
Not available
S-EPMC4394479 | biostudies-literature
MetabolomicsBranched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming

Macrophages are prominent immune cells in the tumor microenvironment that can be educated into pro-tumoral phenotype by tumor cells to favor tumor growth and metastasis. The mechanisms that mediate a mutualistic relationship between tumor cells and macrophages remain poorly characterized. Here, w...

2022-10-03 | MTBLS4497 | MetaboLights
UnknownDiscovery of novel polysubstituted N-alkyl acridone analogues as histone deacetylase isoform-selective inhibitors for cancer therapy.
Not available
S-EPMC10165928 | biostudies-literature
ProteomicsVincristine resistance reshapes sphingolipid composition and promotes mitochondrial complex I deficiency in acute myelogenous leukemia
Modifications in sphingolipid (SL) metabolism and mitochondrial bioenergetics are key factors implicated in cancer cell response to chemotherapy, including chemotherapy resistance. Vinca alkaloids such as vincristine (VCR), widely used in cancer treatment, are no exception, as their beneficial actio...
ORGANISM(S): Homo Sapiens (human) 
2022-04-21 | PXD025645 | JPOST Repository
ProteomicsAn aspartyl pseudoprotease dominates the secretory hydrolase landscape of the skin commensal Malassezia in situ
Malassezia globosa is abundant and prevalent on sebaceous areas of the human skin. Genome annotation reveals that M. globosa possesses a repertoire of secreted hydrolytic enzymes relevant for lipid and protein metabolism on the skin. In-gel proteomics identifies a predicted aspartyl protease, MGL_33...
ORGANISM(S): Cellular Organisms 
2023-11-23 | PXD042508 | JPOST Repository
UnknownPlasma Epstein-Barr Viral Deoxyribonucleic Acid Predicts Worse Outcomes in Pediatric Nonmetastatic Nasopharyngeal Carcinoma Patients: An Observational Study of 89 Cases in an Endemic Area.
Not available
S-EPMC5058881 | biostudies-literature
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