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UnknownSAPS3 subunit of protein phosphatase 6 is an AMPK inhibitor and controls metabolic homeostasis upon dietary challenge in male mice.
Not available
S-EPMC10011557 | biostudies-literature
Unknownp53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake.
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S-EPMC6510239 | biostudies-literature
ProteomicsSAPS3 is an AMPK inhibitor and controls metabolic homeostasis upon dietary challenge
Inhibition of AMPK is tightly associated with metabolic perturbations upon over nutrition, yet the molecular mechanism underneath that is not clear. Here, we demonstrate serine/threonine-protein phosphatase 6 regulatory subunit 3, SAPS3, is a negative regulator of AMPK. SAPS3 is induced under high ...
ORGANISM(S): Homo sapiens (Human) 
2023-01-26 | PXD039625 | Pride
Human 
UnknownMiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.
Not available
S-EPMC6379428 | biostudies-literature
Unknownα-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer.
Not available
S-EPMC7442208 | biostudies-literature
UnknownDietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.
Not available
S-EPMC7335172 | biostudies-literature
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