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MetabolomicsMetabolic mapping of the human solute carrier superfamily

Solute carrier (SLC) transporters govern most of the chemical exchange across cellular membranes and are integral to metabolic regulation, which in turn is linked to cellular function and identity. Despite their key role, individual functions of the SLC superfamily members were not evaluated syst...

2025-07-22 | MTBLS11393 | MetaboLights
ProteomicsMyeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity
In this study, we found that myeloid PTEN can determine chemotherapy responsiveness by promoting NLRP3-dependent antitumor immunity and suggest that it might be a potential biomarker to predict the chemotherapy responses and manipulating NLRP3/IL-1might be able to overcome the chemotherapy resista...
ORGANISM(S): Homo Sapiens 
2020-04-16 | PXD018597 |
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