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ProteomicsProteomic analysis of cellular soluble proteins from human bronchial smooth muscle cells by combining nondenaturing micro 2DE and quantitative LC-MS/MS: Preparation of more than 4000 native protein maps
Soluble proteins of human bronchial smooth muscle cells (HBSMC) were separated by nondenaturing micro 2DE and a 30 mm X 40 mm area of the CBB-stained slab gel (1.0 mm thick) was cut into 1.1 mm X 1.1 mm squares, then the proteins in the 972 gel pieces (squares) were applied to quantitative LC-MS/MS....
ORGANISM(S): Homo sapiens (Human) 
2015-08-10 | PXD001471 | Pride
Cellular proteins Native protein map Nondenaturing micro 2de Lc-ms/ms Quantitative protein-protein interaction 
TranscriptomicsTranscription profiling of Arabidopsis NFYA5 mutant vs wild type
NFYA5 is a transcription factor important for drought resistance. Drought stress up-regulates NFYA5 gene expression not only at the transcriptional level but also at the posttranscriptional level by down-regulating the expression of miR169a that targets NFYA5 transcript for cleavage. Experiment Ove...
ORGANISM(S): Arabidopsis thaliana 
2008-10-21 | E-GEOD-12029 | biostudies-arrayexpress
UnknownMembers of miR-169 family are induced by high salinity and transiently inhibit the NF-YA transcription factor.
Not available
S-EPMC2670843 | biostudies-literature
MetabolomicsAnalysis of fecal microbiome and metabolome changes in goats with pregnant toxemia

Pregnancy toxemia is a common disease, which occurs in older ewes that are pregnant with multiple lambs in the third trimester. Most of the sick goats die within a few days, which can seriously impact the economic benefits of goat breeding enterprises. The disease is believed to be caused by maln...

2024-10-01 | MTBLS7519 | MetaboLights
ProteomicsiTRAQ-based quantitative proteomic analysis reveals potential virulence factors of Erysipelothrix rhusiopathiae
Erysipelothrix rhusiopathiae is a small, facultatively aerobic, gram-positive bacterium that causes erysipelas in swine and a wide spectrum of diseases in other animals, as well as the skin disease erysipeloid in humans. Swine erysipelas caused by E. rhusiopathiae is the most prevalent and economica...
ORGANISM(S): Erysipelothrix rhusiopathiae 
2017-03-28 | PXD005505 | Pride
Comparative proteomics Cell wall proteins Erysipelothrix rhusiopathiae Virulence factor 
UnknownDownregulated RBM5 Enhances CARM1 Expression and Activates the PRKACA/GSK3β Signaling Pathway through Alternative Splicing-Coupled Nonsense-Mediated Decay.
Not available
S-EPMC10778212 | biostudies-literature
TranscriptomicsExpression data of sorted GFP+ and tdTomato+ prostate tumor cells from Pten/Smad4/mTmG mice
Single cells from Ptenpc-/-Smad4pc-/-mTmG+ prostate tumors were isolated into single cells which were FACS-sorted for GFP+ and Tomato+ cells and RNA was purified with TRIzol (Life Technologies). RNA expression profiling was performed using the Mouse Genome 430 2.0 Array (Affymetrix) to generate a P...
ORGANISM(S): Mus musculus 
2016-02-03 | E-GEOD-71319 | biostudies-arrayexpress
UnknownGenetic and functional analyses detect an EXT1 splicing pathogenic variant in a Chinese hereditary multiple exostosis (HME) family.
Not available
S-EPMC8922959 | biostudies-literature
UnknownThe miR-873/NDFIP1 axis promotes hepatocellular carcinoma growth and metastasis through the AKT/mTOR-mediated Warburg effect.
Not available
S-EPMC6556606 | biostudies-literature
UnknownFOXA1 inhibits prostate cancer neuroendocrine differentiation.
Not available
S-EPMC5509480 | biostudies-literature
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