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TranscriptomicsFoxo1 target genes in mouse T cells
CD4+ and CD8+ T cells isolated from wild-type and Foxo1-deficient mice were analyzed by global gene expression profiling with Affymetrix array MOE 430 2.0. Results indicate Foxo1 regulates the expression of genes encoding positive regulators of T cell activation, differentiation, homeostasis, cell a...
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-15037 | biostudies-arrayexpress
GenomicsNovel Foxo1-dependent Transcriptional Programs Control Treg Cell Function [ChIP-Seq]
Regulatory T (Treg) cells characterized by expression of the transcription factor forkhead box P3 (Foxp3) maintain immune homeostasis by suppressing self-destructive immune responses1-4. Foxp3 operates as a late acting differentiation factor controlling Treg cell homeostasis and function5, whereas ...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-40656 | biostudies-arrayexpress
MetabolomicsEnvironmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice
Exposure to environmental chemicals during windows of development is a potentially contributing factor in gut microbiota dysbiosis, and linked to chronic diseases and developmental disorders. We used a community-level model of microbiota metabolism to investigate the effects of diethylhexyl phthalat...
2022-01-17 | MTBLS861 | MetaboLights
TranscriptomicsTranscription profiling of Puga- tBHQ and arsenic treated GCLM-WT and KO mice
Evaluate the protective effect of prior tBHQ treatment from arsenic damage at two dosage levels of arsenic (2 and 20 uM), and compare to the effect of tBHQ or arsenic treatment given alone.
ORGANISM(S): Mus musculus 
2005-12-08 | E-MEXP-371 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat kidney exposed to different doses of Cisplatin- ILSI-HESI NephroToxicity Study - Cisplatin
Evaluation and comparison of biological responses of rats and gene expression responses of the kidney in rats exposed to different doses of Cisplatin [CAS:15663-27-1;CHEBI:27899]
ORGANISM(S): Rattus norvegicus 
2007-01-10 | E-TOXM-11 | biostudies-arrayexpress
TranscriptomicsNovel Foxo1-dependent Transcriptional Programs Control Treg Cell Function [Affymetrix gene expression data]
Regulatory T (Treg) cells characterized by expression of the transcription factor forkhead box P3 (Foxp3) maintain immune homeostasis by suppressing self-destructive immune responses1-4. Foxp3 operates as a late acting differentiation factor controlling Treg cell homeostasis and function5, whereas ...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-40655 | biostudies-arrayexpress
TranscriptomicsIdentification of WRKY22 direct targets under submergence in Arabidopsis with ChIP
To identify direct targets of WRKY22, we created a transgenic Arabidopsis line that expresses a c-myc epitope-tagged WRKY22 and used ChIP followed by microarray hybridization (ChIP-chip) to screen for candidates and validate the in vivo protein-DNA interactions with ChIP followed by quantitative PCR...
ORGANISM(S): Arabidopsis thaliana 
2013-07-03 | E-GEOD-40138 | biostudies-arrayexpress
UnknownComprehensive multi-omic profiling of somatic mutations in malformations of cortical development.
Not available
S-EPMC9961399 | biostudies-literature
UnknownWHO global research priorities for traditional, complementary, and integrative (TCI) medicine: an international consensus and comparisons with LLMs.
Not available
S-EPMC12615007 | biostudies-literature
UnknownAssociations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.
Not available
S-EPMC6323610 | biostudies-literature
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