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GenomicsChIP-seq of WT(with 35S-SUC2 transgene) and proMBD7::gMBD7:4xMYC transgenic plants
In eukaryotes, heterochromatin is characterized by numerous epigenetic marks, including DNA methylation. Spreading of these marks into nearby active genes must be avoided in order to maintain appropriate gene expression. Here, we uncover Arabidopsis Methyl-CpG-Binding Domain 7 (MBD7) and Increased D...
ORGANISM(S): Arabidopsis thaliana 
2015-01-29 | E-GEOD-58789 | biostudies-arrayexpress
TranscriptomicsYeast expression data from conditions that inhibit sirtuins
Sir2 is an NAD+-dependent histone deacetylase, and is the founding member of a large, phylogentically conserved, family of such deacetylases called the Sirtuins. The budding yeast, Saccharomyces cerevisiae, harbors 4 paralogs of Sir2, known as Hst1, Hst2, Hst3, and Hst4. Reducing the intracellular N...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-10 | E-GEOD-18488 | biostudies-arrayexpress
GenomicsGenome-wide Analysis of Functional Sirtuin Chromatin Targets in Yeast
Sir2 and the homologous proteins, Hst1, Hst2, Hst3, and Hst4 from Saccharomyces cerevisiae are NAD+-dependent histone deacetylases of the sirtuin protein family. Sir2 functions in transcriptional silencing at the silent mating-type loci, telomeres, and rDNA locus, but also promotes replicative lifes...
ORGANISM(S): Saccharomyces cerevisiae 
2013-05-10 | E-GEOD-41415 | biostudies-arrayexpress
UnknownClinical profiling and prognosis of out-of-hospital cardiac arrest in ST-segment elevation myocardial infarction in an Asian population.
Not available
S-EPMC12723052 | biostudies-literature
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