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TranscriptomicsInvestigation of endothelial cell gene dysregulation in early pulmonary arterial hypertension disease model
Endothelial cell (EC) dysfunction plays a key role in the pathogenesis of pulmonary arterial hypertension (PAH). To avoid cell cultures and whole lung tissue samples, we have, for the first time, used CD31 antibody coated magnetic beads in conjunction with genome scale RNA expression microarrays to ...
ORGANISM(S): Rattus norvegicus 
2014-02-06 | E-GEOD-42767 | biostudies-arrayexpress
TranscriptomicsChIP-chip of BMP2 or control treated human pulmonary artery endothelial cells with anti-beta-catenin or anti-ppar-gamma antibodies on promoter regions
Reduced bone morphogenetic protein receptor (BMPR)2 expression in patients with pulmonary arterial (PA) hypertension (PAH), can impair PA endothelial cell (EC) function. We now characterize, in human PAECs, a novel BMPR2-mediated transcriptionally active complex between peroxisome proliferator-activ...
ORGANISM(S): Homo sapiens 
2011-05-25 | E-GEOD-29489 | biostudies-arrayexpress
UnknownGlobal surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.
Not available
S-EPMC5879496 | biostudies-literature
UnknownThe histology of brain tumors for 67 331 children and 671 085 adults diagnosed in 60 countries during 2000-2014: a global, population-based study (CONCORD-3).
Not available
S-EPMC8485444 | biostudies-literature
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