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TranscriptomicsDifferential Expressions of miRNAs in resting and activated human in vitro-differentiated NK cells
To investigate miRNA expressions of miRNA upon activation. In vitro-differentiated human NK cells were freshly incubated in the presence of IL15 after 24h deprivation of IL-15. The cells were harvested at the times (0h, resting-Sample 1 and 2; 6h, activated-Sample 3 and 4) and analyzed by microarray...
ORGANISM(S): Homo sapiens 
2011-11-21 | E-GEOD-32411 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human nasal NK/T-cell Lymphoma (8 tumor samples, 2 cell lines)
A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 8 NKTCL biopsies, 2 NKTCL cell lines. Biopsies and cell lines of NK/T-cell lymphoma, nasal-type (NKTCL) were subject to combine...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-791 | biostudies-arrayexpress
ProteomicsKey regulatory roles of PRDM1 in human NK-cell differentiation and activation
PRDM1, encoding a transcription factor (TF), regulates plasma cell and CD8+ T-cell terminal differentiation and Th2 lineage specification, while its role in human NK-cell differentiation and homeostasis is largely unknown. Here, we employed a multi-omics approach to dissect the transcriptional contr...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD069044 | Pride
Prmd1 Mass spectrometry Proximity labeling Nk-cells 
TranscriptomicsTranscription profiling by array of human non anaplastic T-cell lymphoma biopsies and cell lines
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 7 NKTCL biopsies, 2 NKTCL cell lines (SNK6, SNT8), 16 PTCL NOS biopsies, 2 NK cells samples | Biopsies and cell lines of NK/T-cell lymphoma, na...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-TABM-702 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human resting and IL2 activated natural killer cells
The aim of the study was to investigate the activation of human NK cells by IL2 through analyzing the global gene expression at different time points (0, 2, 8 and 24 hours) after culture with the cytokine IL2 at 100 IU/ml. NK cells with the CD56+/CD16+ and CD3- phenotype were negatively selected by ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-8059 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Nipponbare rice roots over a time course of potassium deprivation
Potassium (K+) is one of the most important nutrient ions in plant cells and play crucial roles in many plant physiological and developmental processes. K+ deficiency is the common abiotic stress in natural environment, which inhibits plant growth and reduces production of crops. We used microarrays...
ORGANISM(S): Oryza sativa japonica 
2012-10-31 | E-GEOD-37161 | biostudies-arrayexpress
UnknownIFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella.
Not available
S-EPMC8099885 | biostudies-literature
TranscriptomicsGlobal transcriptomic changes following N-deprivation in Nannochloropsis oceanica IMET1: Illumina sequencing
Limited systems-level understanding of oil synthesis in wild oleaginous algae has hindered the development of microalgal feedstock. Nannochloropsis is a small unicellular microalgae widely distributed in oceans and fresh water. In many large-scale and pilot-scale outdoor cultivation facilities, Nann...
ORGANISM(S): Nannochloropsis oceanica 
2014-05-14 | E-GEOD-42508 | biostudies-arrayexpress
TranscriptomicsCritical Role of STAT5 Transcription Factor Tetramerization for Cytokine Responses and Normal Immune Function (RNA)
Cytokine-activated STAT proteins dimerize and bind to high-affinity motifs, and N-terminal domain-mediated oligomerization of dimers allows tetramer formation and binding to low-affinity tandem motifs, but the functions of dimers versus tetramers are unknown. We generated Stat5a and Stat5b double kn...
ORGANISM(S): Mus musculus 
2012-04-24 | E-GEOD-36888 | biostudies-arrayexpress
TranscriptomicsGene expression data from phosphinothricin (PPT) treated Medicago truncatula root nodules
Nitrogen assimilation in plants is a tightly regulated process that integrates developmental and environmental signals. The legume-rhizobial symbiosis results in the formation of a specialized organ called root nodule, where the rhizobia fixes atmospheric nitrogen into ammonia. Ammonia is assimilate...
ORGANISM(S): Medicago truncatula 
2012-05-08 | E-GEOD-34155 | biostudies-arrayexpress
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