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Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
Data from ProteomeXchange, PXD ID: PXD001636. File: C1_1_TR1.mzml. Published as part of J Immunol. 2015 Sep 25 . From the Abstract: {{i}} Tissues accommodate defined numbers of dendritic cells (DCs) in highly specific niches where different intrinsic and environmental stimuli control DC life span a...
ORGANISM(S): Mus_musculus_viruses, Mouse 
Sus scrofa (pig, or swine) is one of the most important economic animals and a close biological model for complex human diseases such as obesity and diabetes. It is therefore utterly important to decode the porcine microRNAome (miRNAome) as in the literature only a small portion of it is known. In t...
ORGANISM(S): Sus scrofa 
Porcine induced pluripotent stem cells (piPSCs) could serve as a great model system for human stem cell pre-clinical research. However, the pluripotency gene network of piPSCs, especially the function for the core transcription factor ESRRB, was poorly understood. Here, we constructed ESRRB-overexpr...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-17 | PXD027539 | Pride
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