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TranscriptomicsFY-hESC Micro-array raw data
Human embryonic stem cells (hESCs) exhibit a skewed X chromosome inactivation (XCI) have recently been reported. Whether there is any copy number variation (CNV), loss of heterozygousity (LOH) and single nucleotide variant (SNV) in those epigenetically distinct cells and whether these abnormalities ...
ORGANISM(S): Homo sapiens 
2014-10-01 | E-MTAB-1992 | biostudies-arrayexpress
GenomicsWhole genome bisulfite sequencing of idm1, rdd, ros1 mutants and Col-0 WT
Using whole genome bisulfite sequencing to provide single-base resulution of DNA methylation status in ros1, idm1, and rdd mutants and identify hypermethylated regions comparing to wild type Arabidopsis plants. Examination of 3 different mutants' methylome. 8 samples (3 mutants, 1 WT, each has two b...
ORGANISM(S): Arabidopsis thaliana 
2012-06-17 | E-GEOD-33071 | biostudies-arrayexpress
TranscriptomicsMeDIP-chip of zdp mutant
Using meDIP-chip to provide methylation profile in zdp mutant and identify hypermethylated regions comparing to wild type Arabidopsis plants. Examination of zdp mutant's methylome. 4 samples(1 mutant, 1 WT, each has two biological replicates)
ORGANISM(S): Arabidopsis thaliana 
2012-03-20 | E-GEOD-33719 | biostudies-arrayexpress
GenomicsMethylC-Seq of Ws background wild-type (WT), ape1l-1 (Ws background), arp-1 (Col-0 background) and zdp-1 (Col-0 background) mutants
Using MethylC-Seq to provide single-base resolution of DNA methylation status in Ws background wild-type (WT), ape1l-1 (Ws background), arp-1 (Col-0 background) and zdp-1 (Col-0 background) mutants MethylC-Seq: 1 WT and 3 mutants examined, Ws background wild-type (WT), ape1l-1 (Ws background), arp-1...
ORGANISM(S): Arabidopsis thaliana 
2014-11-21 | E-GEOD-52983 | biostudies-arrayexpress
MetabolomicsCardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy
Succinate dehydrogenase, which is known as mitochondrial complex II, has proven to be a fascinating machinery, attracting renewed and increased interest in its involvement in human diseases. Herein, we find that succinate dehydrogenase assembly factor 4 (SDHAF4) is downregulated in cardiac muscle in...
2022-08-12 | MTBLS4579 | MetaboLights
MetabolomicsDefective cytokinin signaling reprograms lipid and flavonoid gene-to-metabolite networks to mitigate high salinity in Arabidopsis

Cytokinin (CK) in plants regulates both developmental processes and adaptation to environmental stress. Arabidopsis histidine phosphotransfer ahp2,3,5 and type-B response regulator arr1,10,12 triple mutants are almost completely defective in CK signaling, and the ahp2,3,5

2021-11-25 | MTBLS2532 | MetaboLights
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