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Bioactive components of Mongolian medicinal Gentiana dahurica Fisch. flowers inhibit the NF-κB signaling pathway and ameliorate chronic obstructive pulmonary disease
ORGANISM(S): Mus Musculus 
2026-04-08 | PXD076741 |
Dysregulated cardiac function after sepsis is common in intensive care unit (ICU) and known to predict poor long-term outcome and increase mortality. Effective therapeutic strategies are largely lacking. Moreover, the pathological feature and the molecular mechanism underlying cardiac dysfunction in...
ORGANISM(S): Mus Musculus 
2023-04-14 | PXD041530 |
Quantitative proteomic analysis raw data for the manuscript entitled “A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy”.
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-01-22 | PXD060051 |
The Hippo pathway plays important roles in organ development, tissue homeostasis, and tumor growth, and its downstream effector TAZ is a transcriptional coactivator that promotes target gene expression through the formation of biomolecular condensates. However, the mechanisms that regulate the biop...
ORGANISM(S): Homo Sapiens 
2023-02-17 | PXD040257 |
This project presents the proteomic profiling of protein complexes associated with the transcription factor TCF21, achieved through affinity purification coupled with mass spectrometry (AP-MS). The study aimed to comprehensively map the TCF21 interactome in two distinct cellular models: the human co...
ORGANISM(S): Homo Sapiens 
2025-12-12 | PXD071976 |
The negative elongation factor (NELF) is essential in establishing RNA Polymerase II (Pol II) pausing at promoter-proximal regions, providing a key regulatory checkpoint for precise gene expression control. In response to heat shock (HS) stress, NELF has been observed to form nuclear condensates, bu...
ORGANISM(S): Homo Sapiens 
2025-05-21 | PXD064175 |
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