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UnknownrMVP: A Memory-efficient, Visualization-enhanced, and Parallel-accelerated Tool for Genome-wide Association Study.
Not available
S-EPMC9040015 | biostudies-literature
MetabolomicsThe gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis
The gut microbiota plays an important role in parasite-host interactions and the induction of immune defense responses. Trichinella spiralis is an important zoonotic parasite that can directly or indirectly interact with the host in the gut. Changes in the gut microbiota following infection with T. ...
2023-08-07 | MTBLS7603 | MetaboLights
ProteomicsProteomic data of Stenotrophomonas maltophilia
S. maltophilia was exposed to a simulated microgravity (SMG) environment in high-aspect ratio rotating-wall vessels bioreactors for 14 days, while the control group was performed in the same bioreactors under normal gravity (NG) environment. After that, combined phenotypic, genomic, transcriptomic a...
ORGANISM(S): Stenotrophomonas maltophilia 
2021-04-30 | PXD025290 | Pride
Stenotrophomonas maltophilia  proteomic 
UnknownGenetic constraint at single amino acid resolution in protein domains improves missense variant prioritisation and gene discovery.
Not available
S-EPMC11238507 | biostudies-literature
TranscriptomicsTwo Supporting Factors Greatly Improve the Efficiency of Human iPS Cell Generation
Human fibroblasts can be induced into pluripotent stem cells (iPS cells), but the reprogramming efficiency is quite low. Here, we screened a panel of candidate factors in the presence of OCT4, SOX2, KLF4 and c-MYC in an effort to improve the reprogramming efficiency from human adult fibroblasts. We ...
ORGANISM(S): Homo sapiens 
2008-11-06 | E-GEOD-12922 | biostudies-arrayexpress
ProteomicsProteome-Wide Deconvolution of Drug Targets and Binding Sites by Lysine Reactivity Profiling
Recently, numerous efforts have been devoted to identifying drug targets and binding sites in complex proteomes, which is of great importance in modern drug discovery. In this study, we developed a robust lysine reactivity profiling method to systematically study drug-binding targets and binding sit...
ORGANISM(S): Homo Sapiens 
PXD045749 |
ProteomicsMass spectrometry analysis of MDD
Proteomics profiling of MDD plasma samples by mass spectrometry in DIA mode
ORGANISM(S): Homo Sapiens 
PXD053331 |
ProteomicsProteomics of cardiac tissue of mice after sepsis model
Dysregulated cardiac function after sepsis is common in intensive care unit (ICU) and known to predict poor long-term outcome and increase mortality. Effective therapeutic strategies are largely lacking. Moreover, the pathological feature and the molecular mechanism underlying cardiac dysfunction in...
ORGANISM(S): Mus Musculus 
2023-04-14 | PXD041530 |
ProteomicsProteomics analysing the exosomes extratced from the BALF of the E.coli or LPS induced acute lung injury (ALI) model
We established E.coli and LPS induced ALI murine model. Then, at 24 hours, the exosome from the BALF were extracted by the Size Exclusion Chromatography (SEC) method and analyzed by quantitive mass spectrometry
ORGANISM(S): Mus Musculus 
PXD046185 |
ProteomicsA chaperone-like function of FUS ensures TAZ condensates dynamics and transcriptional activation
The Hippo pathway plays important roles in organ development, tissue homeostasis, and tumor growth, and its downstream effector TAZ is a transcriptional coactivator that promotes target gene expression through the formation of biomolecular condensates. However, the mechanisms that regulate the biop...
ORGANISM(S): Homo Sapiens 
2023-02-17 | PXD040257 |
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