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Proteomicssystematic proteomic of 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN)
To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to systematic proteomic.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD037295 | Pride
Proteomics Cancer metastasis 
ProteomicsNitric oxide modulates Saccharomyces cerevisiae biofilm formation though regulating the transmembrane protein CTR1 by activating its transcriptional factor MAC1.
Biofilms with immobilized cells in industrial fermentation are beneficial. Encased in extracellular polymeric substance, cells forming biofilms are regulated by various factors. Nitric oxide (NO), as a signaling molecule, recognized as quorum sensing molecule regulating microbe biofilm formation. Re...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-11-12 | PXD010751 | Pride
Transcription factor mac1 Nitric oxide Saccharomyces cerevisiae Biofilm 
UnknownChanges in soluble sugars and the expression of sugar transporter protein genes in strawberry crowns responding to <i>Colletotrichum fructicola</i> infection.
Not available
S-EPMC11646252 | biostudies-literature
ProteomicsProteomics reveals the inhibitory mechanism of Levodopa against esophageal squamous cell carcinoma
The high recurrence rate and poor survival prospects of esophageal squamous cell carcinoma (ESCC) patients after treatment make the ongoing research on chemoprevention drugs for ESCC particularly important. In helping to solve this problem, we screened a large number of FDA-approved drugs and found ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013824 | Pride
Mitochondria Levodopa Chemoprevention Esophageal squamous cell carcinoma (escc) 
UnknownCalf Circumference and All-Cause Mortality: A Systematic Review and Meta-Analysis Based on Trend Estimation Approaches.
Not available
S-EPMC12280773 | biostudies-literature
ProteomicsA proteomic analysis of lysine crotonylation in systemic lupus erythematosus patients
Posttranslational modification (PTM) refers to the process of the covalent processing of translated proteins, as well as the activities and functions of proteins, and it is involved in almost all cellular pathways and processes. Lysine crotonylation (Kcr) is a recently identified PTM and plays a key...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD012966 | Pride
Posttranslational modification Lysine crotonylation Lc-ms/ms 
ProteomicsIdentification of Key Proteins and Pathways in Myocardial Infarction Using Machine Learning Approaches
Acute myocardial infarction (AMI) is a leading cause of global morbidity and mortality, requiring deeper insights into its molecular mechanisms for improved diagnosis and treatment. This study combines proteomics, multi-omics, and machine learning (ML) to identify key proteins and pathways associate...
ORGANISM(S): Homo Sapiens 
PXD062794 |
ProteomicsLysine 2-hydroxyisobutyrylatome profiling reveals extensive lysine 2-hydroxyisobutyrylation in common wheat
In this work, we first analyzed wheat (Triticum aestivum L.) lysine Khib sites by mass spectrometry. A total of 3,348 lysine modification sites from 1,047 proteins were identified in wheat seedlings. The identified Kcr proteins were discovered to be widespread. Bioinformatic data indicated these Kcr...
ORGANISM(S): Triticum aestivum (Wheat) 
2022-12-31 | PXD012666 | Pride
Triticum aestivum l.  post-translational modification  lysine 2-hydroxyisobutyrylation  mass spectrometry  function 
UnknownCytosolic peptides encoding CaV1 C-termini downregulate the calcium channel activity-neuritogenesis coupling.
Not available
S-EPMC9120191 | biostudies-literature
ProteomicsTumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks Nuclear Factor-κB activation in hepatocellular carcinoma
Background: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. Methods: The expression of TNFAIP1 in...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD016378 | Pride
Protein kinase casein kinase ii beta Hepatocellular carcinoma Nuclear factor-κb Tumor suppressor Tumor necrosis factor α-induced protein 1 
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