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ProteomicsN-Glycosylation profiling in rice
As a ubiquitous and essential posttranslational modification occurred in both plants and animals, protein N-linked glycosylation regulates various important biological processes. Unlike the well studied animal N-glycoproteomes, the landscape of rice N-glycoproteome remains largely unexplored. Here, ...
ORGANISM(S): Oryza sativa (Rice) 
2025-05-07 | PXD054828 | Pride
N-glycosylation Rice 
ProteomicsN-glycoproteome profiling of rice
Metabolic glycan labeling (MGL) is a technique that utilizes bioorthogonal chemical reporters to investigate protein glycosylation. While this method has been widely used for glycoproteomic profiling in animals, its application in N-glycoproteomic research in crops remains limited and requires furth...
ORGANISM(S): Oryza sativa (Rice) 
2025-05-07 | PXD056001 | Pride
Metabolic glycan labeling (mgl) N-glycosylation Rice 
TranscriptomicsCOUP-TFII regulates human endometrial stromal genes involved in inflammation
Although the function of COUP-TFII in uterine decidualization has been described in mice, its role in the human uterus remains unknown.To interrogate the role of COUP-TFII in human endometrial function, we utilized a siRNA-mediated loss of function approach in primary human endometrial stromal cells...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-47052 | biostudies-arrayexpress
ProteomicsThe BPAN disease protein WDR45 forms condensates with Caprin-1 to regulate stress granule disassembly
Beta-propeller protein-associated neurodegeneration (BPAN) is a rare X-linked neurodegenerative disorder primarily caused by mutations in the WD repeat domain 45 (WDR45) gene. While WDR45 has traditionally been linked to autophagy, our study uncovers a previously unrecognized role for WDR45 as a cri...
ORGANISM(S): Homo Sapiens 
2025-04-14 | PXD062911 |
GenomicsGenome-wide Profiling of NR2F2 (COUP-TFII) Binding in Human Endometrial Stromal Cells [ChIP-Seq]
ChickenM-BM- ovalbumin upstream promoter-transcription factor II (COUP-TFII; NR2F2) is an orphan nuclear receptor involved in cell-fate specification, organogenesis, angiogenesis and metabolism. Ablation of COUP-TFII in the mouse uterus causes infertility due to defects in embryo attachment and impa...
ORGANISM(S): Homo sapiens 
2013-11-02 | E-GEOD-52008 | biostudies-arrayexpress
TranscriptomicsRobust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non-Small-Cell Lung Cancer Patients
The requirement of frozen tissues for microarray experiments limits the clinical usage of genome-wide expression profiling using microarray technology. The goal of this study is to test the feasibility of developing lung cancer prognosis gene signatures using genome-wide expression profiling of form...
ORGANISM(S): Homo sapiens 
2011-08-31 | E-GEOD-29013 | biostudies-arrayexpress
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