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UnknownSingle-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue.
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S-EPMC7539140 | biostudies-literature
TranscriptomicsExpression data from MDA-MB-231 cells treated with vehicle or YW3-56
PAD4 is overexpressed in many cancer cells. We developed PAD inhibitors that efficiently inhibit the cancer cell growth. One inhibitor YW3-56 could efficiently induce cell death of triple negative breast cancer MDA-MB-231 cells. We used microarray to detail the global gene expression of MDA-MB-231 b...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-46590 | biostudies-arrayexpress
UnknownCritical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture.
Not available
S-EPMC6939474 | biostudies-literature
TranscriptomicsIdentification of miR-181 target genes and a common prognostic gene signature in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30258 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptome profiling of wild soybean (Glycine soja) roots under NaHCO3 treatment
Plant roots are the primary site of perception and injury for saline-alkaline stress. The current knowledge of the saline-alkaline stress transcriptome is most focused on salt (NaCl) stress. Only a little alkaline (NaHCO3) stress transcriptome is limited to one time point after stress. Time-course a...
ORGANISM(S): Glycine soja 
2010-08-14 | E-GEOD-17883 | biostudies-arrayexpress
TranscriptomicsAlkaline-stress response in Glycine soja leaf identifies specific transcription factors and ABA-mediated signaling factors
Transcriptome of Glycine soja leaf tissue during a detailed time course formed a foundation for examining transcriptional processes during NaHCO(3) stress treatment. Of a total of 2,310 detected differentially expressed genes, 1,664 genes were upregulated and 1,704 genes were downregulated at variou...
ORGANISM(S): Glycine soja 
2010-10-13 | E-GEOD-20323 | biostudies-arrayexpress
TranscriptomicsIdentification of prognostic gene signatures in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30285 | biostudies-arrayexpress
UnknownCutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection.
Not available
S-EPMC4761481 | biostudies-literature
UnknownSynthesis, Evaluation, and Mechanism Study of New Tepotinib Derivatives as Antiproliferative Agents.
Not available
S-EPMC6470795 | biostudies-literature
UnknownIdentification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.
Not available
S-EPMC3595425 | biostudies-literature
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