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TranscriptomicsA Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-mediated mRNA Translation
Increasing evidence suggests that Long non-coding RNAs (LncRNAs) represent a new class of regulators of stem cells. However, the roles of LncRNAs in stem cell maintenance and myogenesis remain largely unexamined. For this study, hundreds of novel intergenic LncRNAs were identified that are expresse...
ORGANISM(S): Mus musculus 
2015-08-11 | E-GEOD-68842 | biostudies-arrayexpress
ProteomicsStructural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing
Protein samples were analyzed by Multidimensional Protein Identification Technology (MudPIT), as described previously. Briefly, precipitated proteins were resuspended in 30uL of 100mM Tris pH 8.5 with 8M urea to denature proteins. Cysteines were reduced and alkylated prior to digestion with recombi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-11 | MSV000087403 | MassIVE
ProteomicsCross-tissue deep profiling of redox proteome in obese mice
Cellular redox state, the balance between oxidation and reduction, is precisely regulated through cysteine thiol modification. In this study, we developed a novel method, in conjunction with directed data-independent acquisition (dDIA) for identifying and quantifying a substantial number of sulfhydr...
ORGANISM(S): Mus Musculus 
PXD066139 |
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