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GenomicsGenome-wide analysis of histone marks in E(z) temperature sensitive cells [ChIP-seq]
PcG protein complex PRC2 is a methyltransferase specific for histone H3 lysine27, and H3K27me3 is essential for stable transcription silencing. Less well known but quantitatively much more important is the genome-wide role of PRC2 that dimethylates ~70% of total H3K27. Here we show that H3K27me2 occ...
ORGANISM(S): Drosophila melanogaster 
2015-05-14 | E-GEOD-64219 | biostudies-arrayexpress
GenomicsGenome-wide analysis of epigenetic marks in E(z) temperature sensitive cells [ChIP-seq]
PcG protein complex PRC2 is a methyltransferase specific for histone H3 lysine27, and H3K27me3 is essential for stable transcription silencing. Less well known but quantitatively much more important is the genome-wide role of PRC2 that dimethylates ~70% of total H3K27. Here we show that H3K27me2 occ...
ORGANISM(S): Drosophila melanogaster 
2015-05-14 | E-GEOD-61308 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of three PcG proteins and of histone H3 trimethylated at Lys 27 in Drosophila
We determined the distribution of three PcG proteins: PC, PSC and E(Z), and of histone H3 trimethylated at Lys 27 by chromatin immunoprecipitation (ChIP) coupled with analysis of immunoprecipitated DNA with a high density genomic tiling microarray (Affymetrix).
ORGANISM(S): Drosophila melanogaster 
2006-12-30 | E-MEXP-535 | biostudies-arrayexpress
UnknownThe complete chloroplast genome of Dendrocalamus liboensis Hsueh & D. Z. Li 1985 and its phylogenetic analysis.
Not available
S-EPMC10810639 | biostudies-literature
UnknownHuman genomic Z-DNA segments probed by the Z alpha domain of ADAR1.
Not available
S-EPMC2677879 | biostudies-literature
UnknownMYC drives left-handed Z-DNA formation to shape gene expression.
Not available
S-EPMC12780141 | biostudies-literature
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownBifunctional iron-catalyzed alkyne Z-selective hydroalkylation and tandem Z-E inversion via radical molding and flipping.
Not available
S-EPMC11452693 | biostudies-literature
TranscriptomicsMulti-layer dosage compensation of the avian Z chromosome (bulk RNA-seq)
Sex-chromosome dosage compensation represents a challenge for heterogametic species to maintain correct proportion of gene products across chromosomes in each sex. While therian mammals (XX/XY system) achieve near-perfect balance of X-chromosome mRNAs through X-upregulation and X-inactivation, birds...
ORGANISM(S): Gallus gallus 
2025-06-29 | E-MTAB-14443 | biostudies-arrayexpress
UnknownZ-Selective olefin metathesis reactions promoted by tungsten oxo alkylidene complexes.
Not available
S-EPMC3244563 | biostudies-literature
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