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ProteomicsTrim32-DPEP2 axis is an inflammatory switch of macrophages in intestinal inflammation
The mechanisms that mediate inflammatory macrophages in intestinal inflammation are incompletely understood. Here, using merged analysis of RNA sequences and mass spectrometry (MS)-based quantitative proteomics, we report the distinction of proteomics and transcriptomics in activated macrophage. Dip...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-28 | PXD057405 | Pride
Intestinal inflammation  dpep2  macrophage  vim  map3k7  trim32 
ProteomicsLC-MS/MS on BMSCs affected by E.faecalis supernatants
protenomic analysis on BMSCs infected by E.faecalis
ORGANISM(S): Rattus Norvegicus 
2020-02-09 | PXD017438 |
ProteomicsTurboID-based proximity labeling identifies reticulon-like protein B2 as a pro-viral factor coopted for the biogenesis of viral replication organelles in plants
Although intensive studies have been performed to identify and characterize host factors involved in viral replication complex formation, the high dynamism of this process and the insoluble properties of the complex make it difficult to be analyzed comprehensively using traditional affinity purifica...
ORGANISM(S): Nicotiana Benthamiana 
2023-02-12 | PXD040073 |
ProteomicsProteomics and lipidomics analysis of plasma biomarkers for cervical cancer
This study leverages integrated proteomic and lipidomic analyses on plasma samples from 115 high-grade squamous intraepithelial lesion (HSIL) patients, 133 CC patients, and 88 healthy controls (CT) and develops robust models for effectively predicting HSIL and CC.
ORGANISM(S): Homo Sapiens 
2025-05-13 | PXD063876 |
ProteomicsProxitome profiling of a viral suppressors of RNA silencing identifies the DEAD-box RNA helicase RH20 as a positive regulator of antiviral RNA interference in Nicotiana benthamiana
In the prolonged arms race between viruses and their host plants, viruses usually encode viral suppressors of RNA silencing (VSR) to overcome the hosts' defense mechanism by inhibiting RNAi. Barley stripe mosaic virus (BSMV) is an RNA virus characterized by a positive single-stranded genetic structu...
ORGANISM(S): Nicotiana Benthamiana 
2024-02-20 | PXD049705 |
ProteomicsLC-MS based on TurboID proximity labeling technology: Screening for interacting proteins of AL7 and their differences
TurboID tags were fused to AL7 protein, and adjacent interacting proteins were enriched by biotin. The interacting proteins were identified by mass spectrometry after protein extraction, and the differences of interacting proteins before and after TMV treatment were analyzed
ORGANISM(S): Nicotiana Benthamiana 
2025-02-18 | PXD060894 |
ProteomicsDeep metaproteomics of inflammatory bowel diseases
Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is associated with a loss or an imbalance of host-microbe interactions. Depletion-assisted deep metaproteomics was employed to reveal disease-specific networks of host-microbial protein associations in IBD...
ORGANISM(S): Homo Sapiens 
2023-06-28 | PXD043380 |
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