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ProteomicsProteomic research on effect of EIF4A1 inhibition in MYC-amplified Group 3 medulloblastoma
As the most life-threatening subtype of pediatric medulloblastoma (MB), MYC-amplified Group 3 (G3) MB lacks effective and selective therapeutics. We tried to indirectly target MYC (oncogenic driver and cancer-dependent molecule) production via inhibiting translational machinery. Through multiple dat...
ORGANISM(S): Homo Sapiens 
2020-10-15 | PXD022014 |
ProteomicsMultiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression
Our study provides an enabling technology and rich data resources to expand the understanding of transmembrane proteome organization and dynamics in the brain as well as accelerate the discovery of potential therapeutic targets for depression treatment.
ORGANISM(S): Mus Musculus 
2021-07-26 | PXD027559 |
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