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ProteomicsGenome-scale CRISPRi screen identifies pcnB repression conferring overproduction of free fatty acids in Escherichia coli
In this study, we carried out genome-scale CRISPRi modulation combining fluorescence-activated cell sorting (FACS) and next-generation sequencing (NGS) to identify genetic determinants for FFAs overproduction in Escherichia coli. The pcnBi (AP) strain that repressed the expression of pcnB produced 2...
ORGANISM(S): Escherichia Coli 
2024-05-18 | PXD052390 |
ProteomicsTime-resolved lung proteome profiling in an LPS-induced acute lung injury mouse model
This project investigates the dynamic lung proteome in a murine model of lipopolysaccharide (LPS)-induced acute lung injury (ALI). C57BL/6N mice were exposed to LPS via intratracheal nebulization to induce ALI, and lung tissues were collected at multiple time points (non-stimulated controls, and day...
ORGANISM(S): Mus Musculus 
2025-12-06 | PXD071688 |
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