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GenomicsA genome-wide approach to delineate novel XBP-1 targets involved in liver metabolism
This experiment was conducted to identify novel XBP-1 targets involved in liver metabolism. The following abstract from the submitted manuscript describes the major findings of this work. The IRE1a-XBP1s axis regulates the COPII-mediated secretory program in response to nutrient availability. Lin Li...
ORGANISM(S): Mus musculus 
2019-06-03 | GSE101202 | GEO
TranscriptomicsRNA-seq analysis of liver transcriptomes from wild type and Ern1-LKO mice
This experiment was conducted to identify mRNA transcripts alteration in liver of Ern1 liver specific knockout mice. The following abstract from the submitted manuscript describes the major findings of this work. The IRE1a-XBP1s axis regulates the COPII-mediated secretory program in response to nutr...
ORGANISM(S): Mus musculus 
2019-06-03 | GSE100358 | GEO
TranscriptomicsSelect correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis
We report abonormally expressed genes of idiopathic interstitial pneumonia by RNA-seq analysis. BMP3 was found down-regulated in idiopathic intestital pneumonia patients, and it closely correlated with pathogenesis of disease. The role of BMP3 in advancement of idiopathic interstitial pneumonia was ...
ORGANISM(S): Homo sapiens 
2015-09-19 | E-GEOD-73189 | biostudies-arrayexpress
GenomicsMus musculus
A genome-wide approach to delineate novel XBP-1 targets involved in liver metabolism
PRJNA393859 | ENA
TranscriptomicsGenome-wide profiling of E12.5 cardiomyocytes RNA expression in both heterozygous control and mutant
Congenital heart disease is among the most frequent major birth defects. Epigenetic marks are crucial for organogenesis, but their role in heart development is poorly understood. Polycomb Repressive Complex 2 (PRC2) trimethylates histone H3 at lysine 27, establishing H3K27me3 repressive epigenetic m...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-29992 | biostudies-arrayexpress
TranscriptomicsCardiac transcription factors in HL-1 cells: gene expression and genome binding profiling
[1] Gene expression profiling in Gata4, Mef2a knockdown in HL-1 cells. HL-1 cells infected with adenovirus expressing either control siRNA or Gata4, and Gata4 & Mef2a siRNA. [2] Genome-wide maps of cardiac transcription factors binding region in HL-1 cells. We performed bio-ChIP-seq using streptavi...
ORGANISM(S): Mus musculus 
2011-03-02 | E-GEOD-21529 | biostudies-arrayexpress
GenomicsMus musculus
RNA-seq analysis of liver transcriptomes from wild type and Ern1-LKO mice
PRJNA391445 | ENA
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