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UnknownValidation of Urine-based Gene Classifiers for Detecting Bladder Cancer in a Chinese Study.
Background: Current standard methods used to detect and monitor bladder cancer (BC) are invasive or have low sensitivity. We have previously reported in an international European study four non-invasive tests for BC diagnosis based on the gene expression patterns of urine. Objective: t...
S-EPMC6134826 | biostudies-literature
UnknownGenomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia.
Genomic landscapes of 92 adult and 111 pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL) were investigated using next-generation sequencing and copy number alteration analysis. Recurrent gene mutations and fusions were tested in an additional 87 adult and 93 pediatric patients. Amo...
S-EPMC4919728 | biostudies-literature
UnknownTranscriptome analysis reveals a comprehensive insect resistance response mechanism in cotton to infestation by the phloem feeding insect Bemisia tabaci (whitefly).
The whitefly (Bemisia tabaci) causes tremendous damage to cotton production worldwide. However, very limited information is available about how plants perceive and defend themselves from this destructive pest. In this study, the transcriptomic differences between two cotton cultivars that exhibit ei...
S-EPMC5042180 | biostudies-literature
UnknownOrganic-inorganic hybrid piezotronic bipolar junction transistor for pressure sensing.
With the rapid development of the Internet of Things (IoTs), wearable sensors are playing an increasingly important role in daily monitoring of personal health and wellness. The signal-to-noise-ratio has become the most critical performance factor to consider. To enhance it, on the one hand, good se...
S-EPMC11189938 | biostudies-literature
UnknownCharacterization of the complete chloroplast genome of Chinese privet Ligustrum lucidum (Oleaceae).
Ligustrum lucidum is a species of privet native to the southern half of China. It is often used as an ornamental tree, sometimes as a cultivar. In present study, we reported the Ligustrum lucidum chloroplast (cp) genome. The total chloroplast genome size of L. lucidum was 154,79...
S-EPMC7800634 | biostudies-literature
UnknownGenome-Wide Analysis of Cotton miRNAs During Whitefly Infestation Offers New Insights into Plant-Herbivore Interaction.
Although the regulatory function of miRNAs and their targets have been characterized in model plants, a possible underlying role in the cotton response to herbivore infestation has not been determined. To investigate this, we performed small RNA and degradome sequencing between resistant and suscept...
S-EPMC6861988 | biostudies-literature
UnknownSIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression.
The cGAS/STING cytosolic DNA-sensing pathway plays a significant role in antitumor immunity. Expression of STING is tightly regulated and commonly reduced or defective in many types of cancer. We have identified SIX4 as a significant regulator of STING expression in colon cancer cells. We showed tha...
S-EPMC10680432 | biostudies-literature
UnknownPolymorphisms in C-reactive protein and Glypican-5 are associated with lung cancer risk and Gartrokine-1 influences Cisplatin-based chemotherapy response in a Chinese Han population.
The role of genetics in progression of cancer is an established fact, and susceptibility risk and difference in outcome to chemotherapy may be caused by the variation in low-penetrance alleles of risk genes. We selected seven genes (CRP, GPC5, ACTA2, AGPHD1, SEC14L5, RBMS3, and GKN1) that previously...
S-EPMC4426656 | biostudies-literature
UnknownDynamic interplay of atherogenic index and body roundness in cardio-renal-metabolic disease: a multi-state analysis.
Not available
S-EPMC12821189 | biostudies-literature
UnknownRiluzole Enhancing Anti-PD-1 Efficacy by Activating cGAS/STING Signaling in Colorectal Cancer.
Colorectal cancer is the second leading cause of cancer mortality in the United States. Although immune checkpoint blockade therapies including anti-PD-1/PD-L1 have been successful in treating a subset of patients with colorectal cancer, the response rates remain low. We have found that riluzole, a ...
S-EPMC11695182 | biostudies-literature
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