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MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
ProteomicsProteomic sequencing of atrial fibrosis rat model caused by chronic intermittent hypoxia
This study was aimed to understand the changes of proteins occurring in atrial tissue of atrial fibrillation (AF) rat model based on proteome sequencing.SD rats were used for AF model construction by chronic intermittent hypoxia (CIH) induction. The tissue pathological changes were observed by hemat...
ORGANISM(S): Rattus Norvegicus 
PXD042312 |
ProteomicsPotential binding partners of NUDT13 in DLD-1
To explore the role of NUDT13 in the initiation and progression of CRC, we performed NUDT13 immunoprecipitation in DLD-1 following LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens 
PXD041430 |
ProteomicsNEAT1 Regulates BMSCs Aging Through Disruption of FGF2 Nuclear Transport
Background: The aging of bone marrow mesenchymal stem cells (BMSCs) impairs bone tissue regeneration, contributing to skeletal disorders. LncRNA NEAT1 is considered as a proliferative inhibitory role during cellular senescence, but the relevant mechanisms remain insufficient. This study aims to eluc...
ORGANISM(S): Homo Sapiens 
2025-01-16 | PXD059860 |
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