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MetabolomicsTherapeutic effects of traditional Chinese medicine compound Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota

Hua-Feng-Dan is a traditional Chinese medicine compound used to treat ischemic stroke, but little is known about its therapeutic mechanism. This study explored whether and how the mechanism involves readjustment of gut microbiota. Rats were subjected to middle cerebral artery occlusion as a model...

2025-01-06 | MTBLS10818 | MetaboLights
UnknownThe O-glycosylating enzyme GALNT2 acts as an oncogenic driver in non-small cell lung cancer.
Not available
S-EPMC9440866 | biostudies-literature
ProteomicsVessel-on-a-Chip Coupled Proteomics Reveal Pressure-Overload-Induced Vascular Remodeling
We developed a vessel-on-a-chip to mimic both physiological and pathological stretch, along with a mouse model of hypertension. We applied proteomics analysis to investigate the changes in vascular smooth muscle cells using the vessel-on-a-chip system and changes in hypertensive mice.
ORGANISM(S): Mus Musculus 
2024-11-08 | PXD057724 |
TranscriptomicsExpression changes in IC GABA receptors in the auditory midbrain of young adult and aging presbycusis mice.
We performed a microarray analysis of auditory midbrain (inferior colliculus, IC) mRNA from young adult CBA mice (controls) with good hearing, middle aged (MA) with good hearing, and old mild (MP) and severe (SP) presbycusic CBA mice. Fold Change data derived from RMA normalization revealed that the...
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-49522 | biostudies-arrayexpress
ProteomicsTargeting the Golgi apparatus enhances PD-L1 blockade and synergizes with oxaliplatin to improve immunotherapy efficacy
Proteomic profiling of differentially expressed proteins of 4T1 cells induced by liposome.
ORGANISM(S): Mus Musculus 
2026-02-03 | PXD073979 |
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