Sort   by:  
 Page size 
GenomicsGenome Wide Mapping of Foxo1 Binding-sites in Murine T Lymphocytes
The Forkhead box O (Foxo) family of transcription factors has a critical role in controlling the development, differentiation, and function of T cells. However, the direct target genes of Foxo transcription factors in T cells have not been well characterized. In this study, we focused on mapping the...
ORGANISM(S): Mus musculus 
2014-08-19 | E-GEOD-60470 | biostudies-arrayexpress
TranscriptomicsTranscription Factor Foxo1 Controls Memory CD8+ T Cell Responses To Infection [Affymetrix]
Memory T cells provide immunity against pathogen reinvasion, but mechanisms of their long-term maintenance is unclear. Here we show that mice with the deletion of the transcription factor Foxo1 in activated CD8+ T cells had defective secondary but not primary responses to Listeria monocytogenes inf...
ORGANISM(S): Mus musculus 
2013-05-16 | E-GEOD-46942 | biostudies-arrayexpress
GenomicsNovel Foxo1-dependent Transcriptional Programs Control Treg Cell Function [ChIP-Seq]
Regulatory T (Treg) cells characterized by expression of the transcription factor forkhead box P3 (Foxp3) maintain immune homeostasis by suppressing self-destructive immune responses1-4. Foxp3 operates as a late acting differentiation factor controlling Treg cell homeostasis and function5, whereas ...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-40656 | biostudies-arrayexpress
GenomicsTranscription Factor Foxo1 Controls Memory CD8+ T Cell Responses To Infection [ChIP-Seq]
Memory T cells provide immunity against pathogen reinvasion, but mechanisms of their long-term maintenance is unclear. Here we show that mice with the deletion of the transcription factor Foxo1 in activated CD8+ T cells had defective secondary but not primary responses to Listeria monocytogenes inf...
ORGANISM(S): Mus musculus 
2013-05-16 | E-GEOD-46943 | biostudies-arrayexpress
TranscriptomicsNovel Foxo1-dependent Transcriptional Programs Control Treg Cell Function [Affymetrix gene expression data]
Regulatory T (Treg) cells characterized by expression of the transcription factor forkhead box P3 (Foxp3) maintain immune homeostasis by suppressing self-destructive immune responses1-4. Foxp3 operates as a late acting differentiation factor controlling Treg cell homeostasis and function5, whereas ...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-40655 | biostudies-arrayexpress
Sort   by:  
 Page size