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TranscriptomicsArray-based comparative genomic hybridization study of human embryonic stem cell lines
G-banding of human embryonic stem cells (hESC) has proved their predisposition to aneuploidy of chromosomes 12, 17 and X. Now, using array-based comparative genomic hybridization, we find that hESC also accumulate other recurrent chromosomal abnormalities, such as duplications of stemness genes, sub...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-13422 | biostudies-arrayexpress
TranscriptomicsSingle-cell aneuploidy detection by array CGH
In this study, we extend array CGH technology by making the accurate detection of chromosomal imbalances possible from a single fibroblast and blastomere following Phi29 DNA polymerase amplification. Firstly, array CGH experiments were performed on four different fibroblast cell lines, derived from ...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-3642 | biostudies-arrayexpress
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