Ligament - OmicsDI

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Unknown (5218)
Genomics (352)
Transcriptomics (324)
Proteomics (50)
Other (7)
Metabolomics (6)
Methylation profiling (2)
Clinical (1)

Organisms

Homo sapiens (248)
Mus musculus (95)
Rattus norvegicus (25)
Aerococcus urinae NBRC 15544 = CCUG 36881 (25)
Andropogon gerardi (25)
Bacteria (25)
Bartonella quintana JK 31 (25)
Canis lupus familiaris (25)
Sus scrofa (7)
Danio rerio (4)
Oryctolagus cuniculus (3)
Lupinus albus (1)
Canis lupus familiaris (1)
Mus musculus cytomegalovirus 2 (1)
Tannerella forsythia (1)
Betapolyomavirus hominis (1)
Betapolyomavirus macacae (1)
Merkel cell polyomavirus (1)
Human alphaherpesvirus 2 (1)
JC polyomavirus (1)
human gammaherpesvirus 4 (1)
Human alphaherpesvirus 1 (1)
Human gammaherpesvirus 8 (1)
Human immunodeficiency virus 1 (1)
Porphyromonas gingivalis (1)
Salmo salar (1)
Equus caballus (1)
Human betaherpesvirus 5 (1)
Murid gammaherpesvirus 4 (1)
Murid betaherpesvirus 1 (1)

Organisms

Homo sapiens (158)
Mus musculus (64)
Rattus norvegicus (20)
Sus scrofa (5)
Danio rerio (4)
Equus caballus (2)
Salmo salar (1)

Repository

ENA (319)
geo (215)
biostudies-arrayexpress (144)
pride (25)
MassIVE (10)
iProX (9)
MetaboLights (6)
EGA (4)
jPOST (4)
ExpressionAtlas (2)
GPMDB (1)
PAXDB (1)
PeptideAtlas (1)

Tissue

Stem cell (8)
Cell culture (7)
Periodontal ligament (6)
Fibroblast (3)
Primary cell (2)
Tendon (2)
Deciduous periodontal ligament (1)
Permanent periodontal ligament (1)
Others (1)
Blood plasma (1)
Blood serum (1)
Connective tissue (1)
Connective tissue cell (1)
Dental pulp (1)
Dental pulp cell (1)
Femorotibial joint (1)
Gingival epithelial cell (1)
Lens nucleus (1)
Mesenchymal stem cell of Wharton's jelly (1)
Mesenchymal stem cell of adipose (1)
Osteoblast (1)
Rheumatoid arthritis disease specific synovial fluid (1)
Synovia (1)
Tooth (1)

Disease

Osteoarthritis (3)
Normal (2)
Periodontitis (2)
Post-traumatic osteoarthritis (1)
Immuno-osseus dysplasiaspondyloenchondrodysplasia (SPENCD) (1)
Regional block (1)
Not Available (1)
Connective tissue disease (1)
Disease free (1)
Obesity (1)
Parkinson's disease (1)
Periodontal disease (1)
Rheumatoid arthritis (1)

Technology Type

Mass Spectrometry (25)
Shotgun proteomics (15)
Bottom-up proteomics (8)
Mass spectrometry (4)
Data-dependent acquisition (2)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Data-independent acquisition (1)
Gel-based experiment (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (9)
Illumina HiSeq 2500 (8)
Orbitrap Fusion Lumos (4)
Illumina NovaSeq X (2)
NA (2)
Illumina HiSeq 2000 (2)
NextSeq 500 (2)
Q Exactive Plus (2)
Liquid Chromatography MS - positive - reverse phase (2)
Liquid Chromatography MS - negative - reverse phase (2)
DNBSEQ Eukaryotic Stranded Transcriptome library preparation- Stranded mRNA Library (1)
Single nuclei were captured using the 10x Genomics Chromium Controller. (1)
FACSAria III (1)
HP desktop (1)
Fluidics workstation (1)
Truseq RNA v2 (1)
GeneChip Scanner 3000 7G (1)
Scanning hardware (1)
NextSeq 2000 (1)
DNBSEQ-T7 (1)
BGISEQ-500 (1)
Ion Torrent S5 XL (1)
Illumina HiSeq 4000 (1)
Instrument (1)
LTQ Orbitrap Elite (1)
LTQ Orbitrap Velos (1)
Q Exactive (1)
Thermo Scientific Q-Exactive Mass Spectrometer (Thermo Fisher Scientific, Bremen, Germany) coupled to a Thermo Ultimate 3000 RSLC nano HPLC system (1)
Liquid Chromatography MS - negative (1)
Liquid Chromatography MS - positive (1)

Publication Date

2026 (47)
2022 (35)
2021 (33)
2025 (32)
2024 (29)
2013 (28)
2014 (25)
2023 (23)
2020 (19)
2016 (18)
2012 (16)
2019 (14)
2018 (13)
2010 (13)
2008 (13)
2011 (12)
2007 (12)
2017 (9)
2009 (8)
2015 (7)
2005 (2)
2006 (2)
2004 (1)

UNIPROT ID/AC

9823.ENSSSCP00000000410 (1)
9823.ENSSSCP00000000606 (1)
9823.ENSSSCP00000000717 (1)
9823.ENSSSCP00000001244 (1)
9823.ENSSSCP00000002108 (1)
9823.ENSSSCP00000003829 (1)
9823.ENSSSCP00000003865 (1)
9823.ENSSSCP00000005050 (1)
9823.ENSSSCP00000005769 (1)
9823.ENSSSCP00000007309 (1)
9823.ENSSSCP00000008216 (1)
9823.ENSSSCP00000009166 (1)
9823.ENSSSCP00000009441 (1)
9823.ENSSSCP00000009732 (1)
9823.ENSSSCP00000011053 (1)
9823.ENSSSCP00000011561 (1)
9823.ENSSSCP00000012903 (1)
9823.ENSSSCP00000013237 (1)
9823.ENSSSCP00000014399 (1)
9823.ENSSSCP00000015012 (1)
9823.ENSSSCP00000016046 (1)
9823.ENSSSCP00000016065 (1)
9823.ENSSSCP00000018879 (1)
9823.ENSSSCP00000019251 (1)
9823.ENSSSCP00000019299 (1)
9823.ENSSSCP00000019489 (1)
9823.ENSSSCP00000019502 (1)
9823.ENSSSCP00000019566 (1)
9823.ENSSSCP00000019793 (1)
9823.ENSSSCP00000020128 (1)

ENSEMBL ID

ENSG00000170477 (1)

CHEBI ID

CHEBI:16024 (3)
CHEBI:16857 (3)
CHEBI:70959 (3)
CHEBI:37024 (3)
CHEBI:17750 (3)
CHEBI:15971 (3)
CHEBI:18050 (3)
CHEBI:16015 (3)
CHEBI:17268 (3)
CHEBI:16737 (3)
CHEBI:16919 (3)
CHEBI:16414 (3)
CHEBI:17191 (3)
CHEBI:15354 (3)
CHEBI:16643 (3)
CHEBI:17295 (3)
CHEBI:30769 (3)
CHEBI:16493 (2)
CHEBI:17626 (2)
CHEBI:75014 (2)
CHEBI:50392 (2)
CHEBI:18077 (2)
CHEBI:78737 (2)
CHEBI:16802 (2)
CHEBI:73026 (2)
CHEBI:28123 (2)
CHEBI:16742 (2)
CHEBI:9349 (2)
CHEBI:16530 (2)
CHEBI:18323 (2)

Metabolite Name

Betaine (3)
Benzoic acid (3)
Choline (3)
Taurine (3)
D-Mannose (3)
L-Glutamine (3)
Uracil (3)
Linoleic acid (3)
Cytidine (3)
Xanthine (3)
Uridine (3)
Creatinine (3)
Creatine (3)
L-Valine (3)
Hippuric acid (3)
L-Phenylalanine (3)
1-Deoxy-D-xylulose 5-phosphate (2)
Aminoadipic acid (2)
Ala-Thr (2)
Pelargonic acid (2)
D-Pipecolinic acid (2)
All-trans-Retinoic acid (2)
PC(16:0/16:0) (2)
Methylsuccinic acid (2)
L-Carnosine (2)
3-Methylhistidine (2)
N-Acetylglutamine (2)
Urocanic acid (2)
1-Aminocyclopropanecarboxylic acid (2)
Pyruvic acid (2)

First Public Date

2026 (53)
2024 (40)
2025 (39)
2022 (35)
2014 (33)
2021 (32)
2023 (26)
2020 (22)
2019 (12)
2018 (10)
2017 (7)
2016 (7)
2015 (3)

Study status

Recruiting (1)

Study type

Transcription profiling by array (94)
RNA-seq of coding RNA (22)
RNA-seq of non coding RNA (5)
ChIP-seq (3)
MicroRNA profiling by array (3)
Unknown experiment type (2)
Animal - High-throughput sequencing (2)
Cell line - High-throughput sequencing (2)
ChIP-chip by array (2)
Transcription profiling by RT-PCR (2)
RNA-seq of coding RNA from single cells (2)
RNA-seq of total RNA (2)
RIP-seq (1)
Other (1)
Single nucleus RNA sequencing (1)
Interventional (1)

Release Date

2025 (788)
2022 (750)
2023 (659)
2024 (553)
2021 (549)
2020 (424)
2019 (314)
2017 (273)
2018 (229)
2016 (176)
2014 (134)
2015 (130)
2026 (94)
2013 (88)
2012 (68)
2010 (32)
2011 (29)
2009 (24)
2008 (16)
2007 (15)
2005 (4)
2006 (4)
2003 (3)
2000 (3)
2002 (1)
1999 (1)

Lab affiliation

Assistant Professor, Physiology and Pharmacology, University of Calgary, McCaig Insitute for Bone and Joint Health (1)
Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (1)
Department of Biology Wanek School of Natural Sciences High Point University 1 N University Pkwy High Point, NC 27368 USA (1)
Department of Clinical Sciences, Cornell University, Ithaca, NY, USA Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA (1)
Department of Diagnosis and Surgery, School of Dentistry at Araraquara, Sao Paulo State University - UNESP, Araraquara, São Paulo, Brazil (1)
Department of Diagnosis and Surgery, School of Dentistry at Araraquara, Sao Paulo State University - UNESP, Araraquara, São Paulo, Brazil. (1)
Department of Musculoskeletal Biology Institute of Ageing and Chronic Disease University of Liverpool (1)
Department of Pathology and Proteomics Center, Boston Children's Hospital, Harvard Medical School, MA, USA (1)
Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, University of Campinas, Brazil (1)
Department of Rehabilitation Medicine, Nanfang Hospital of Southern Medical University, Guangzhou 510000, China. (1)
Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou, China, 510515 (1)
Deptartment of Orthodontics, University Clinic of Dental Medicine, University of Geneva (1)
Erciyes University Genome and Stem Cell Center (GENKOK) (1)
Hangzhou Women's Hospital, Hangzhou, China (1)
Head musculoskeletal skeletal biology department, institute of ageing and chronic disease, University of Liverpool, UK (1)
Head of the Laboratory of non-coding DNA, Institute of Cytology RAS, St. Petersburg, Russia (1)
Karolinska Institutet (1)
Mass Spectrometry and Proteomics Facility (1)
NIH/NIDCR (1)
Oral Biology (International Program), Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand (1)
School of Biomedical Sciences, University of Plymouth, UK (1)
The Forsyth Institute (1)
University of Liverpool (1)
University of science and technology beijing (1)
head of Laboratory of Regenerative Biomedicine, Institute of Cytology, Russian Academy of Sciences (1)

Location

China (1)

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Determining predictive metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament disease

OBJECTIVES: This study used hydrogen nuclear magnetic resonance spectroscopy (1H NMR) for the first-time to examine differences in the metabolomic profile of stifle joint synovial fluid from dogs with cranial cruciate ligament rupture with and without meniscal injuries, in order ...

2025-08-14 | MTBLS6050 | MetaboLights

AMPK activation orchestrated replicative senescence of periodontal ligament stem cells via regulating metabolomics

BACKGROUND: Periodontal ligament mesenchymal stem cells (PDLSCs) are a promising cell resource for cell-based regenerative medicine in dentistry. PDLSCs inevitably acquire a senescent phenotype after prolonged in vitro expansion, and the key regulators of cells during replicative...

2022-11-15 | MTBLS4568 | MetaboLights

Comparative gene expression analysis of dental follicle and periodontal ligament in humans

The aim of this study was to evaluate and compare the gene expression profiles of dental follicle and periodontal ligament in humans, which can possibly explain their functions of dental follicle and PDL such as eruption coordination and stress resorption. That may apply this information to clinical...

ORGANISM(S): Homo sapiens

2014-08-21 | E-GEOD-51342 | biostudies-arrayexpress

Comparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth

There are histological and functional differences between human deciduous and permanent pediodontal ligament (PDL) tissues. The purpose of this study was to determine the differences between these two types of tissue at the molecular level by comparative gene expression analysis. PDL samples were ob...

ORGANISM(S): Homo sapiens

2013-09-06 | E-GEOD-50640 | biostudies-arrayexpress

Transcription profiling of rat severed medial collateral ligament following injury

Gene Expression Profiling of Severed Rat Medial Collateral Ligament at 1, 2, 4, 7,1 0, and 14 days Following Injury with Control and Cultured Ligament Fibroblasts and Rat Universal Reference RNA; The aim of this study was to assess the genes involved in the repair of the the dense connective tissue ...

ORGANISM(S): Rattus norvegicus

2008-04-05 | E-GEOD-10720 | biostudies-arrayexpress

Mouse periodontal ligament tissue after orthodontic tooth movement

Mouse periodontal ligament tissue after orthodontic tooth movement for 14 days. Tissue was dissected by a laser microdissection microscope. Samples were analyzed separately at mesial (compression) and distal (tension) sides.

ORGANISM(S): Mus Musculus (mouse)

2022-12-16 | PXD030430 | JPOST Repository

Transcriptome and Micronome analysis of OPLL

Ossification of the posterior longitudinal ligament (OPLL) is formed by heterogeneous ossification of posterior longitudinal ligament. The patho-mechanism of OPLL is still largely unknown. MicroRNAs are small nucleatides that function as regulators of gene expression in almost any biological process...

ORGANISM(S): Homo sapiens

2016-04-04 | E-GEOD-69787 | biostudies-arrayexpress

Expression data from human periodontal ligament

We used microarrays to detect the differences in gene-expression of the periontal ligament between patients with healthy periodontal ligament and patients with periodontitis RNA was extracted directly from the middle third of the human periodontal ligament

ORGANISM(S): Homo sapiens

2011-03-17 | E-GEOD-27993 | biostudies-arrayexpress

New protein from an unexpected ligament

This study describes the discovery of the gene responsible for differentiation of stem cells into ligament tissue. This important finding may lead to the development of treatments for gonarthrosis, rupture of the cruciate ligament and periodontal ligament, and ossification of the posterior longitudi...

ORGANISM(S): Mus musculus

2013-03-31 | E-GEOD-35269 | biostudies-arrayexpress

Comprehensive proteomic comparison between native tendon and ligament and 3D tissue engineered tendon and ligament constructs

Tendons and ligaments are important biological structures in both humans and animals. They are part of dense connective tissue and are crucial to the functioning of the musculoskeletal system. However, they are commonly damaged due to age-related wear and tear, trauma or sports related incidents, wh...

ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris)

2016-06-27 | PXD003094 | Pride

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