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UnknownThe sialidase NEU1 directly interacts with the juxtamembranous segment of the cytoplasmic domain of mucin-1 to inhibit downstream PI3K-Akt signaling.
Not available
S-EPMC8591358 | biostudies-literature
UnknownNeuraminidase 1-mediated desialylation of the mucin 1 ectodomain releases a decoy receptor that protects against Pseudomonas aeruginosa lung infection.
Not available
S-EPMC6333888 | biostudies-literature
TranscriptomicsHTC avian macrophage cells stimulated with 3 species of Eimeria across a 48 hour timecourse
HTC avain macrophage cell line was stimulated with E. tenella, acervulina, and maxima for 0, 4, 18, and 48 hours. Total RNA was extracted, mRNA was purified, and RNA samples were directly labeled with Alexa555 or 647. The experiment was performed in loop format, so that each sample was labeled wit...
ORGANISM(S): Gallus gallus 
2010-06-30 | E-GEOD-3723 | biostudies-arrayexpress
TranscriptomicsImmunoenhancing effects of Montanide adjuvant on recombinant coccidia antigen vaccination against Eimeria spp. and comparative microarray analysis of intestinal lymphocytes
This study utilized comparative global gene expression microarray analysis to evaluate the effects of two different Montanide adjuvants, ISA70 and ISA71, in promoting chicken protective immunity following vaccination with profilin, an actin-regulatory protein that is expressed by multiple Eimeria sp...
ORGANISM(S): Gallus gallus 
2012-09-11 | E-GEOD-40743 | biostudies-arrayexpress
UnknownMUC1 ectodomain is a flagellin-targeting decoy receptor and biomarker operative during Pseudomonas aeruginosa lung infection.
Not available
S-EPMC8608881 | biostudies-literature
TranscriptomicsEffect of dietary supplementation with Curcuma longa (turmeric) during Eimeria maxima and Eimeria tenella infection of chickens
This study utilized comparative global gene expression microarray analysis to evaluate the effects of curcumin on intestinal immunity of chicken. Two-condition experiment, Curcumin-fed chickens vs. Non-treated control chickens. Biological replicates: 2 control replicates, 2 Curcumin-fed replicates w...
ORGANISM(S): Gallus gallus 
2012-05-07 | E-GEOD-37813 | biostudies-arrayexpress
TranscriptomicsEffect of dietary supplementation with Anethol during Eimeria maxima and Eimeria tenella infection of chickens
This study utilized comparative global gene expression microarray analysis to evaluate the effects of Anethol on intestinal immunity of chicken. Two-condition experiment, Anethol-fed chickens vs. Non-treated control chickens. Biological replicates: 2 control replicates, 2 Anethol-fed replicates with...
ORGANISM(S): Gallus gallus 
2012-10-02 | E-GEOD-41250 | biostudies-arrayexpress
TranscriptomicsEffect of dietary supplementation with direct fed microbials (DFM) in chicken
This study utilized comparative global gene expression microarray analysis to evaluate the effects of DFM on intestinal immunity of chicken. Two-condition experiment, DFM-fed chickens vs. Non-treated control chickens. Biological replicates: 2 control replicates, 2 DFM-fed replicates with dye-switchi...
ORGANISM(S): Gallus gallus 
2012-11-01 | E-GEOD-41934 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcriptional changes in the Clostridium perfringens-afflicted chicken intestine in an avian necrotic enteritis (NE) disease model
This study utilized comparative global gene expression microarray analysis to evaluate the effects of NE on intestinal immunity of chicken. Two-condition experiment, NE-afflicted chickens vs. Non-infected control chickens. Biological replicates: 2 control replicates, 2 NE-afflicted replicates with d...
ORGANISM(S): Gallus gallus 
2013-09-26 | E-GEOD-51154 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Expression Profiles in Broiler Chickens with Gangrenous Dermatitis (GD)
This study utilized comparative global gene expression microarray analysis of GD-affected and clinically healthy chickens from a recent GD outbreak to glean insights into the molecular and cellular changes associated with this disease process. Two-condition experiment, GD-affected vs. Healthy chicke...
ORGANISM(S): Gallus gallus 
2010-10-27 | E-GEOD-24939 | biostudies-arrayexpress
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