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UnknownNovel missense mutation affecting the LIM-A domain of LMX1B in a family with Nail-Patella syndrome.
Not available
S-EPMC6409120 | biostudies-literature
TranscriptomicsComparison of stem/progenitor cell number and transcriptomic profile in mammary tissue of dairy and beef breed heifers
Bovine mammary stem cells (MaSC) are a source of ductal and lobulo-alveolar tissue during development of mammary gland and its remodeling in repeating lactation cycles. We hypothesize that the number of MaSC, their molecular properties and interactions with their niche may be essential to determine ...
ORGANISM(S): Bos taurus 
2013-06-16 | E-GEOD-47816 | biostudies-arrayexpress
GenomicsGenome-wide chromatin-immunoprecipitation studies of purified SAN cells reveals critical direct targets of ISL1 and suggests potential co-factor families for ISL1 action in SAN cells
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-68974 | biostudies-arrayexpress
MetabolomicsMetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Mouse liver assays)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-02 | MTBLS1266 | MetaboLights
TranscriptomicsMEi vs BM-MSC
The aim of the experiment is to compare the transcriptional profile of MEi (mesenchymal-like mucoepidermoid tumor) cells with BM-MSCs (bone marrow mesenchymal stromal cells). The MEi cells were isolated from a mucoepidermoid tumor from the trachea. BM-MSCs were isolated from bone marrow of healthy d...
ORGANISM(S): Homo sapiens 
2015-01-20 | E-MTAB-2093 | biostudies-arrayexpress
TranscriptomicsGenome-wide mRNA expression analyses revealed dysregulation of genes important for SAN function in Hcn4-CreERT2;Isl1 mutants.
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-24 | E-GEOD-69097 | biostudies-arrayexpress
MetabolomicsMetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Standard mixture assay)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-05 | MTBLS1311 | MetaboLights
UnknownClinical and genetic characterization of basal cell carcinoma and breast cancer in a single patient.
Not available
S-EPMC4149681 | biostudies-literature
UnknownRepair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease.
Not available
S-EPMC4061071 | biostudies-literature
UnknownEffects of spaceflight on the muscles of the murine shoulder.
Not available
S-EPMC5690377 | biostudies-literature
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