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TranscriptomicsGenome-wide mRNA expression analyses revealed dysregulation of genes important for SAN function in Hcn4-CreERT2;Isl1 mutants.
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-24 | E-GEOD-69097 | biostudies-arrayexpress
GenomicsGenome-wide chromatin-immunoprecipitation studies of purified SAN cells reveals critical direct targets of ISL1 and suggests potential co-factor families for ISL1 action in SAN cells
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-68974 | biostudies-arrayexpress
UnknownLIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments.
Not available
S-EPMC7609000 | biostudies-literature
TranscriptomicsRegulation of neurogenin-dependent gene expression by geminin
Transcriptional targets of neurogenin (Ngnr1) were identified by over-expression of an inducible form of neurogenin in Xenopus ectodermal explants. The effects of co-expressing the nucleoprotein geminin on Ngnr1-dependent target gene transactivation were defined. Regulating the transition from line...
ORGANISM(S): Xenopus laevis 
2012-12-06 | E-GEOD-39658 | biostudies-arrayexpress
UnknownCardiovascular Autonomic Dysfunction Predicts Diabetic Foot Ulcers in Patients With Type 2 Diabetes Without Diabetic Polyneuropathy.
Not available
S-EPMC4998383 | biostudies-literature
UnknownThe complete chloroplast genome sequence of Melampyrum koreanum (Orobanchaceae), an endemic and hemi-parasitic herb in Korea.
Not available
S-EPMC8510606 | biostudies-literature
UnknownEndoscopic Ultrasound-Guided Laser Ablation Using a Diffusing Applicator for Locally Advanced Pancreatic Cancer Treatment.
Not available
S-EPMC9102236 | biostudies-literature
UnknownCOVID-19's impact on primary care and related mitigation strategies: A scoping review.
Not available
S-EPMC8293960 | biostudies-literature
UnknownNuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 Transcription.
Not available
S-EPMC6702425 | biostudies-literature
UnknownFirst report of cherry virus A infecting Prunus mume in South Korea.
Not available
S-EPMC5510625 | biostudies-literature
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