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TranscriptomicsGene expression change after LSD1 siRNA treatment in ER-negative breast cancer cells MDA-MB-231
Knock-down of LSD1 using siRNA approach induced regulation of several proliferation-associated genes in ER-negative breast cancer cells MDA-MB-231. To identify changes on gene expression caused by treatment with siRNA directed against LSD1 (si) or control siRNA (control) in MDA-MB-231 cells, total R...
ORGANISM(S): Homo sapiens 
2011-07-19 | E-GEOD-30775 | biostudies-arrayexpress
UnknownAn Fc variant with two mutations confers prolonged serum half-life and enhanced effector functions on IgG antibodies.
Not available
S-EPMC9628495 | biostudies-literature
TranscriptomicsWhy does HAMLET preferentially kill tumor cells? p38-dependent death in tumor but up-regulation of innate immunity in healthy, differentiated cells
HAMLET triggers a p38- and ER stress-dependent death response in carcinoma cells. Transcriptome and proteome analysis detected an increase in p38 expression and phosphorylation exclusively in carcinoma cells and p38 inhibitors delayed the death response to HAMLET in carcinoma and lymphoma cells. ER...
ORGANISM(S): Homo sapiens 
2010-08-24 | E-GEOD-23772 | biostudies-arrayexpress
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