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TranscriptomicsIdentification of LMX1B target genes in a tet-off inducible HeLa cell line and in the mouse kidney
LMX1B is a LIM-homeodomain transcription factor essential for development. Putative LMX1B target genes have been identified through mouse gene targeting studies; however, in the absence of in vivo molecular characterization of their regulation, their identity as direct LMX1B targets remains hypothet...
ORGANISM(S): Homo sapiens 
2008-12-03 | E-GEOD-12008 | biostudies-arrayexpress
TranscriptomicsscRNA-seq from Trex1 KO in tumor
Single-cell RNA-seq data for Trex1 WT and KO mice from the tumor. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
2026-03-25 | E-MTAB-16526 | biostudies-arrayexpress
TranscriptomicsscRNA-seq from Trex1 KO in heart
Single-cell RNA-seq data for Trex1 WT and KO mice from the heart. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
2026-03-25 | E-MTAB-16525 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq from Trex1 KO in heart
Bulk RNA-seq data for Trex1 WT and KO mice from the heart. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
2026-03-25 | E-MTAB-16524 | biostudies-arrayexpress
TranscriptomicsHapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformans
Analysis of the transcriptional response of C. neoformans WT, cir1 mutant, hap3 mutant and hapX mutant to different iron sources. The following experimental design was adopted for the study. Within each strain, each treatment pair (low-iron, +FeCl3, +Transferrin and +Hemin; 6 pairs) were hybridized ...
ORGANISM(S): Cryptococcus neoformans 
2011-04-13 | E-GEOD-22988 | biostudies-arrayexpress
TranscriptomicsMEi vs BM-MSC
The aim of the experiment is to compare the transcriptional profile of MEi (mesenchymal-like mucoepidermoid tumor) cells with BM-MSCs (bone marrow mesenchymal stromal cells). The MEi cells were isolated from a mucoepidermoid tumor from the trachea. BM-MSCs were isolated from bone marrow of healthy d...
ORGANISM(S): Homo sapiens 
2015-01-20 | E-MTAB-2093 | biostudies-arrayexpress
TranscriptomicsThe zinc finger protein Mig1 regulates mitochondrial function and azole drug susceptibility in the pathogenic fungus Cryptococcus neoformans
The opportunistic pathogen Cryptococcus neoformans causes fungal meningoencephalitis in immunocompromised individuals. In previous studies, we found that the Hap complex in this pathogen represses genes encoding mitochondrial respiratory functions and TCA cycle components under low-iron conditions....
ORGANISM(S): Cryptococcus neoformans 
2015-12-17 | E-GEOD-76063 | biostudies-arrayexpress
UnknownMice deficient in STAT1 but not STAT2 or IRF9 develop a lethal CD4+ T-cell-mediated disease following infection with lymphocytic choriomeningitis virus.
Not available
S-EPMC3393544 | biostudies-literature
TranscriptomicsHSB-2 cells stably expressing LDB1 or mutant LDB1 proteins
LMO2 is a component of multisubunit DNA-binding transcription factor complexes that regulate gene expression in hematopoietic stem and progenitor cell development. Enforced expression of LMO2 causes leukemia by inducing hematopoietic stem cell-like features in T-cell progenitor cells, but the bioche...
ORGANISM(S): Homo sapiens 
2015-12-15 | E-GEOD-75839 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of parietal cells isolated from WT and Gastrin Knockout mice to identify genes responsive to gastrin.
Parietal cells were isolated from WT and Gastrin Knockout mice. Targets from three biological replicates of each were generated and the expression profiles were determined using Affymetrix murine U74Av2 arrays. Comparisons between the sample groups allow the identification of genes with gastrin re...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2772 | biostudies-arrayexpress
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