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GenomicsComprehensive Long Span Paired-End-Tag Mapping Reveals Characteristic Patterns of Structural Variations in Epithelial Cancer Genomes
Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long span paired-end-tag (PET) sequencing approach using 10 Kb genomic DNA inserts to study human genome structural variations (SVs). The use of 10 Kb insert size allows the identification of brea...
ORGANISM(S): Homo sapiens 
2011-04-06 | E-GEOD-26954 | biostudies-arrayexpress
UnknownApplication of an ex-vivo drug sensitivity platform towards achieving complete remission in a refractory T-cell lymphoma.
Not available
S-EPMC6985240 | biostudies-literature
UnknownModeling Antibody Kinetics Post-mRNA Booster Vaccination and Protection Durations Against SARS-CoV-2 Infection.
Not available
S-EPMC12327169 | biostudies-literature
GenomicsAn East-Asian polymorphism underlies BCR-ABL mutation-independent resistance to tyrosine kinase inhibitors in chronic myelogenous leukemia
We used massively parallel DNA sequencing of paired-end ditags (DNA-PET) to identify structural genetic factors associated with disease progression and drug-resistance in representative samples from four CML patients and one CML cell line. The functional consequences of our genetic findings were ev...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-28303 | biostudies-arrayexpress
ProteomicsProteomic analysis of human brain organoids
Microglia are specialised brain-resident macrophages that arise from primitive macrophages colonising the embryonic brain. Microglia contribute to multiple aspects of brain development, but their precise roles in early human brain remain poorly understood due to limited access to relevant tissues. T...
ORGANISM(S): Homo sapiens (Human) 
2025-11-26 | PXD044406 | Pride
Organoids Brain Quantitative proteome Microglia 
UnknownGermline Polymorphisms and Length of Survival of Nasopharyngeal Carcinoma: An Exome-Wide Association Study in Multiple Cohorts.
Not available
S-EPMC7237860 | biostudies-literature
UnknownEfficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters.
Not available
S-EPMC9874655 | biostudies-literature
UnknownMeta-analysis confirms the LCE3C_LCE3B deletion as a risk factor for psoriasis in several ethnic groups and finds interaction with HLA-Cw6.
Not available
S-EPMC3386316 | biostudies-literature
UnknownClinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs.
Not available
S-EPMC12075701 | biostudies-literature
UnknownMechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study.
Not available
S-EPMC9791731 | biostudies-literature
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