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ProteomicsExome-based proteogenomics of HEK-293 human cell line: coding genomic variants identified at the level of shotgun proteome
Genomic and proteomic data were integrated into the proteogenomic workflow to identify coding genomic variants of Human Embryonic Kidney 293 (HEK-293) standard cell line at the proteome level. Shotgun proteome data published by Geiger et al (2012) and obtained in this work for HEK-293 were searched ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080712 | MassIVE
TranscriptomicsThe ureic-based herbicide linuron and the model anti-androgen flutamide regulate common gene networks in the fathead minnow (Pimephales promelas) ovary
The herbicide linuron is an endocrine disruptor with a suspected anti-androgenic mode of action (MOA) but the complete MOA for LIN is not fully characterized. The objectives of this study were to better characterize the MOA of LIN in the fathead minnow (FHMs) ovary by comparing expression profiles ...
ORGANISM(S): Pimephales promelas 
2012-07-01 | E-GEOD-38287 | biostudies-arrayexpress
UnknownNeuromuscular control of wingbeat kinematics in Anna's hummingbirds (Calypte anna).
Not available
S-EPMC2892424 | biostudies-literature
UnknownModels to Predict Hepatitis B Virus Infection Among Patients With Cancer Undergoing Systemic Anticancer Therapy: A Prospective Cohort Study.
Not available
S-EPMC7351320 | biostudies-literature
TranscriptomicsTranscription profiling of mouse mammary tumor-initiating cells
Using a syngeneic p53 null mouse mammary gland tumor model that closely mimics human breast cancer, we have identified by limiting dilution transplantation as well as in vitro mammosphere and clonogenic assays a Lin-CD29HighCD24High subpopulation of tumor-initiating cells. Differentially expressed ...
ORGANISM(S): Mus musculus 
2008-10-18 | E-GEOD-8863 | biostudies-arrayexpress
TranscriptomicsEnhancer-bound LDB1 Regulates a Corticotrope Promoter Pausing Repression Program [GRO-seq]
Substantial evidence supports the hypothesis that enhancers are critical regulators of cell type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation and re...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-64515 | biostudies-arrayexpress
GenomicsEnhancer-bound LDB1 Regulates a Corticotrope Promoter Pausing Repression Program [ChIP-seq]
Substantial evidence supports the hypothesis that enhancers are critical regulators of cell type determination, orchestrating both positive and negative transcriptional programs; however, the basic mechanisms by which enhancers orchestrate interactions with cognate promoters during activation and re...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-64483 | biostudies-arrayexpress
TranscriptomicsHigh mitochondrial respiration and glycolytic capacity represent a metabolic phenotype of human tolerogenic dendritic cells
Human monocyte-derived dendritic cells (moDCs) have been used as an in vitro model for studying tolerance and immunity. However, the underlying metabolic states of tolerogenic (dexamethasone and vitamin D3-treated), immature and immunogenic (mature, LPS-treated) moDCs have not been completely charac...
ORGANISM(S): Homo sapiens 
2015-05-08 | E-GEOD-52894 | biostudies-arrayexpress
MetabolomicsIntegration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance
The development of reliable, mixed-culture biotechnological processes hinges on understanding how microbial ecosystems respond to disturbances. Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous microbial populations from a biological wastewater treatment plant. W...
2021-04-06 | MTBLS2021 | MetaboLights
TranscriptomicsCaenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
MicroRNAs are regulators of gene expression whose functions are critical for normal development and physiology. We have previously characterized mutations in a Caenorhabditis elegans microRNA-specific Argonaute ALG-1 (Argonaute-like gene) that are antimorphic [alg-1(anti)]. alg-1(anti) mutants have ...
ORGANISM(S): Caenorhabditis elegans 
2015-09-07 | E-GEOD-72659 | biostudies-arrayexpress
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