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UnknownImproving Small Intestinal Motility in Experimental Acute Necrotising Pancreatitis by Modulating the CPI-17/MLCP Pathway Using Chaiqin Chengqi Decoction.
Not available
S-EPMC7035521 | biostudies-literature
TranscriptomicsThe RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells and Primes Future Gene Activation
Enhancers play a central role in precisely regulating the spatiotemporal expression of developmentally regulated genes. The molecular mechanisms and factors required for controlling the inactive or poised enhancers and their function in future gene activation remain elusive. Here, we have identified...
ORGANISM(S): Mus musculus 
2012-12-30 | E-GEOD-38148 | biostudies-arrayexpress
UnknownAGI grade-guided chaiqin chengqi decoction treatment for predicted moderately severe and severe acute pancreatitis (CAP trial): study protocol of a randomised, double-blind, placebo-controlled, parallel-group, pragmatic clinical trial.
Not available
S-EPMC9644559 | biostudies-literature
GenomicsSuper Elongation Complex (SEC) and global genomic analyses in murine embryonic stem (ES) cells and in human cells in response to activation signals.
Transcriptional regulation of developmentally controlled genes is at the heart of differentiation and organogenesis. In this study, we have performed global genomic analyses in murine embryonic stem (ES) cells and in human cells in response to activation signals. We have identified an essential role...
ORGANISM(S): Mus musculus 
2011-07-19 | E-GEOD-30267 | biostudies-arrayexpress
TranscriptomicsDetermination of transcript abundance before and after serum induction in human HCT-116 colon cancer cell line.
Transcriptional regulation of developmentally controlled genes is at the heart of differentiation and organogenesis. In this study, we have performed mRNA transcript abdundance analyses in human cells in response to serum activation signal by RNA-seq. mRNA transcript abundance determined before and ...
ORGANISM(S): Homo sapiens 
2011-07-19 | E-GEOD-30786 | biostudies-arrayexpress
UnknownNfiR, a New Regulatory Noncoding RNA (ncRNA), Is Required in Concert with the NfiS ncRNA for Optimal Expression of Nitrogenase Genes in Pseudomonas stutzeri A1501.
Not available
S-EPMC6606865 | biostudies-literature
TranscriptomicsExpression analysis on Mll1+/+ and Mll1-/- MEFs
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II A common landmark of activated genes is the presence of trimethylation on lysine 4 of histone H3 (H3K4) ...
ORGANISM(S): Mus musculus 
2009-10-20 | E-GEOD-18261 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of H3K4 methylation
This SuperSeries is composed of the following subset Series: GSE18261: Expression analysis on Mll1+/+ and Mll1-/- MEFs GSE18262: ChIP-chip with antibodies for histone 3 lysine 4 trimethylation and histone 3 in Mll1+/+ and Mll1-/- MEFs GSE18263: ChIP-chip with antibodies for histone 3 lysine 4 trimet...
ORGANISM(S): Mus musculus 
2009-10-20 | E-GEOD-18258 | biostudies-arrayexpress
TranscriptomicsChIP-chip with antibodies for histone 3 lysine 4 trimethylation, histone 3, and PolII in Mll1+/+ and Mll1-/- MEFs
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II A common landmark of activated genes is the presence of trimethylation on lysine 4 of histone H3 (H3K4) ...
ORGANISM(S): Mus musculus 
2010-06-21 | E-GEOD-18264 | biostudies-arrayexpress
TranscriptomicsRetinoids induce rapid dynamic changes in the non-coding RNAs and epigenetic profiles of murine Hox clusters (ChIP-chip)
Physiologically relevant concentrations of retinoic acid are added to Mouse ES cells and a time course (0-72 hours) is examined with tiling array ChIP-chip and RNA-seq to characterize the early dynamics of expression of coding and non-coding RNAs and epigenetics in and around the Hox clusters. Expre...
ORGANISM(S): Mus musculus 
2015-04-27 | E-GEOD-61584 | biostudies-arrayexpress
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