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TranscriptomicsGenome wide gene expression profiles of Drosophila l(3)mbt larval brains and cultured tumors
Mutants in the Drosophila gene lethal (3) malignant brain tumor cause malignant growth in the larval brain. This data shows the changes in gene expression profile associated to mutations in l(3)mbt, both in situ in third instar larval brains and in tumors cultured for 1 5 and 10 (T1, T5, T10) rounds...
ORGANISM(S): Drosophila melanogaster 
2011-02-01 | E-GEOD-24917 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila Myb-MuvB/dREAM
Myb-MuvB (MMB)/dREAM is a nine subunit complex first described in Drosophila as a repressor of transcription, dependent upon E2F2 and the RBFs. Myb, an integral member of MMB, curiously plays no role in the silencing of the test genes previously analyzed. Moreover, Myb plays an activating role in DN...
ORGANISM(S): Drosophila melanogaster 
2008-06-16 | E-GEOD-8751 | biostudies-arrayexpress
TranscriptomicsGenome position and gene amplification - expressional profiling of methotrexate resistant colonies
We investigated the influence of genome position on propensity to amplify. First, we integrated a mutant form of DHFR into different positions in the human genome, challenged cells with methotrexate and then studied the genomic alterations arising in drug resistant cells. We observed site specific d...
ORGANISM(S): Homo sapiens 
2007-10-08 | E-GEOD-6361 | biostudies-arrayexpress
UnknownAlternative splicing of a chromatin modifier alters the transcriptional regulatory programs of stem cell maintenance and neuronal differentiation.
Not available
S-EPMC11126784 | biostudies-literature
UnknownMacrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer.
Not available
S-EPMC4675660 | biostudies-literature
TranscriptomicsGene expression profiling of murine innate lymphoid cells
Innate lymphoid cells (ILCs) are a recently recognized heterogenous group of immune cells that are critical in orchestrating immunity and inflammation in the intestine, but whether ILCs influence immune responses or tissue homeostasis at other mucosal sites remains poorly characterized. Here we iden...
ORGANISM(S): Mus musculus 
2013-04-30 | E-GEOD-46468 | biostudies-arrayexpress
UnknownThe splicing regulators RBM5 and RBM10 are subunits of the U2 snRNP engaged with intron branch sites on chromatin.
Not available
S-EPMC11057915 | biostudies-literature
TranscriptomicsRevisiting Global Gene Expression Analysis (RNA-Seq)
Gene expression analysis is a widely used and powerful method for investigating the transcriptional behavior of biological systems, for classifying cell states in disease and for many other purposes. Recent studies indicate that common assumptions currently embedded in experimental and analytical p...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-40783 | biostudies-arrayexpress
GenomicsCholesterol and Pharmacogenetics (CAP) Study

The Cholesterol and Pharmacogenetics Study was a 6-week open label, non-randomized study of 40mg/day simvastatin treatment in 944 African-American and Caucasian men and women. Plasma lipid and lipoprotein were measured on two occasions prior to treatment and at 4 and 6 weeks of treatment. The stu...

phs000481.v1.p1 | EGA
UnknownRbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1.
Not available
S-EPMC5890944 | biostudies-literature
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