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TranscriptomicsTranscription profiling of mouse 344SQ lung adenocarcinoma cells under forced miR-200 expression
Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here we addressed this question by using tumor cell lines derived from mice that develop metastatic lung adenocarcinoma owing to expression of mutant K-ras and p...
ORGANISM(S): Mus musculus 
2009-11-28 | E-GEOD-15741 | biostudies-arrayexpress
UnknownNucleotide resolution profiling of m7G tRNA modification by TRAC-Seq.
Not available
S-EPMC8959837 | biostudies-literature
TranscriptomicsscRNA-seq from Trex1 KO in heart
Single-cell RNA-seq data for Trex1 WT and KO mice from the heart. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
2026-03-25 | E-MTAB-16525 | biostudies-arrayexpress
TranscriptomicsscRNA-seq from Trex1 KO in tumor
Single-cell RNA-seq data for Trex1 WT and KO mice from the tumor. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
2026-03-25 | E-MTAB-16526 | biostudies-arrayexpress
UnknownAssociation of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.
Not available
S-EPMC5815405 | biostudies-literature
UnknownMettl1/Wdr4-Mediated m7G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation.
Not available
S-EPMC6086580 | biostudies-literature
TranscriptomicsComparative genomic hybridization to map an amplified region in 1q23 in human sarcomas
Mapping of an amplified region in 1q23 in sarcomas using array CGH.
ORGANISM(S): Homo sapiens 
2005-11-01 | E-MEXP-427 | biostudies-arrayexpress
TranscriptomicsCopy number alterations of intracranial tumors
Affymetrix OncoScan data from primary and metastatic intracranial lesions collected for the validation of our intraoperative brain tumor classification with nanopore sequencing. All samples were processed from FFPE by our clinical lab using the standard protocol for clinical samples.
ORGANISM(S): Homo sapiens 
2024-12-17 | E-MTAB-14700 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse 344SQ lung adenocarcinoma cells with high metastatic potential (syngeneic mouse model)
The biologic basis for NSCLC metastasis is not well understood. Here we addressed this deficiency by transcriptionally profiling tumors from a genetic mouse model of human lung adenocarcinoma that develops metastatic disease owing to the expression of K-rasG12D and p53R172H. As a tool to investigate...
ORGANISM(S): Mus musculus 
2009-11-28 | E-GEOD-14458 | biostudies-arrayexpress
GenomicsChIP of BET proteins in iBET resistance [ChIP-seq]
Bromodomain and Extra Terminal protein (BET) inhibitors are first-in-class targeted therapies that deliver a new therapeutic paradigm by directly targeting epigenetic readers1,2. Early clinical trials have shown significant promise especially in acute myeloid leukaemia (AML)3; therefore the evaluati...
ORGANISM(S): Mus musculus 
2015-09-15 | E-GEOD-63682 | biostudies-arrayexpress
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