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TranscriptomicsGene expression changes induced by overexpression of EVI1 in Lin- hematopoietic cells [Lin]
The transcription factor Evi1 is essential for the formation and maintenance of hematopoietic stem cells, and induces clonal dominance with malignant progression upon constitutive activation by chromosomal rearrangements or transgene integration events. To understand the immediate and adaptive respo...
ORGANISM(S): Mus musculus 
2013-01-09 | E-GEOD-34729 | biostudies-arrayexpress
MetabolomicsGlobal metabolomics of fireflies (Coleoptera: Lampyridae) explore metabolic adaptation to fresh water in insects

Aquatic insects are well-adapted to freshwater environments, but metabolic mechanisms of such adaptations, particularly to primary environmental factors (e.g., hypoxia, water pressure, dark light and abundant microbes), are poorly known. Most firefly species (Coleoptera: Lampyridae) are terrestri...

2022-10-03 | MTBLS4987 | MetaboLights
TranscriptomicsGene expression changes induced by overexpression of EVI1 in Lin- hematopoietic cells [EVI1_ST]
The transcription factor Evi1 is essential for the formation and maintenance of hematopoietic stem cells, and induces clonal dominance with malignant progression upon constitutive activation by chromosomal rearrangements or transgene integration events. To understand the immediate and adaptive respo...
ORGANISM(S): Mus musculus 
2013-01-08 | E-GEOD-39103 | biostudies-arrayexpress
GenomicsThe DREAM complex promotes gene body deposition of H2A.Z for target repression
As part of a study of the function of the C. elegans DREAM complex, here we have used ChIP-seq to analyze the patterns of histone variant HTZ-1/H2A.Z and various histone modifications in lin-35(n745) mutants. In addition, we have used RNA-seq to analyze gene expression in lin-35 and htz-1 mutants as...
ORGANISM(S): Caenorhabditis elegans 
2015-04-02 | E-GEOD-62833 | biostudies-arrayexpress
UnknownThermal runaway of Lithium-ion batteries employing LiN(SO2F)2-based concentrated electrolytes.
Not available
S-EPMC7547674 | biostudies-literature
UnknownCharacterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.
Not available
S-EPMC6782594 | biostudies-literature
UnknownPhysiological Mechanisms and Core Genes in Response to Saline-Alkali Stress in Foxtail Millet (<i>Setaria italica</i> L.).
Not available
S-EPMC12190892 | biostudies-literature
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
TranscriptomicsGene expression profiling in WT and Hif1a-/- HSCs
To understand the underlying mechanism by which the Hif1a gene is required by hematopoietic stem cells (HSCs), we performed a comparative DNA microarray analysis using total RNA isolated from wild type Lin-Sca-1+c-Kit+ cells and Hif1a-/- Lin-Sca-1+c-Kit+ cells. The result was validated by quantitati...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-35110 | biostudies-arrayexpress
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