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Despite advances in the development of direct KRAS inhibitors, KRAS-mutant cancers continue to exhibit resistance to the currently available therapies. Here, we identified REGγ as a mutant KRAS-associated factor that enhances REGγ transcription through the KRAS intermediate NRF2, suggesting that the...
ORGANISM(S): Homo Sapiens 
2025-01-01 | PXD059364 |
Calciphylaxis, also known as calcific uremic arteriolopathy (CUA), is a rare disease with high mortality rate. We effectively rescued CUA patients with novel human amnion-derived mesenchymal stem cell (hAMSC) therapy. Due to the heterogeneity of cutaneous lesion, it is imperative to identify non-inv...
ORGANISM(S): Homo Sapiens 
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