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TranscriptomicsMicroarray of 3D cultured basal cells in the presence of Wnt3A
Adult stem cells have the ability to self-renew and to generate specialized cells. Self-renewal is dependent on extrinsic niche factors but few of those signals have been identified. We show that adult mammary glands contain a Wnt-responsive cell population that is enriched for stem cells. In cell c...
ORGANISM(S): Mus musculus 
2014-10-22 | E-GEOD-55117 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse cell lines immune sensitive P0 and immune resistant P3 identifies a tumor immune evasion mechanism using P0 and P3 cell lines
The emergence of immune resistance variants during immunotherapy is poorly understood. We generated a highly immune resistant cell line (P3) from a susceptible cell line (P0) by subjecting it to 3 rounds of in vivo immune selection. Subsequently, microarray analysis of P0 and P3 was performed to i...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2774 | biostudies-arrayexpress
ProteomicsC. elegans as a model for inter-individual variation in metabolism
Fox BW, Ponomarova O, Lee YU, Zhang G, Giese EG, Walker M, Roberto NM, Na H, Reis-Rodrigues P, Curtis BJ, Kolodziej AR, Crombie TA, Zdraljevic S, Yilmaz LS, Andersen EC, Schroeder FC, Walhout AJM (2022) C. elegans as a model for inter-individual variation in metabolism
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2021-07-13 | MSV000087810 | MassIVE
TranscriptomicsMeDIP-chip from clinical cervical tissues in promoters
Utilizing methylation DNA immunoprecipitation (MeDIP) coupled with promoter tiling arrays, we analyzed the methylation profiles of pooled DNA from human cervical carcinoma and normal cervix Cervical carcinoma compaire with normal cervix
ORGANISM(S): Homo sapiens 
2012-08-05 | E-GEOD-33187 | biostudies-arrayexpress
ProteomicsTargeting PILRα, an immune checkpoint mediating T cell suppression, for cancer immunotherapy
One of the most successful therapies in cancer treatment involves immune checkpoint blockade using the anti-programmed death-1 (anti-PD-1)/programmed death-ligand 1 (PD-L1) antibody, which targets the interaction between tumors and T cells. However, the overall response rate is < 30% in patients wit...
ORGANISM(S): Homo Sapiens 
2024-01-25 | PXD048903 |
UnknownTargeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy.
Not available
S-EPMC12810954 | biostudies-literature
UnknownMechanism of Antigen Presentation and Specificity of Antibody Cross-Reactivity Elicited by an Oligosaccharide-Conjugate Cancer Vaccine.
Not available
S-EPMC10161213 | biostudies-literature
UnknownTumor-derived exosomal BCYRN1 activates WNT5A/VEGF-C/VEGFR3 feedforward loop to drive lymphatic metastasis of bladder cancer.
Not available
S-EPMC8288020 | biostudies-literature
UnknownCrystal structures of dimeric and heptameric mtHsp60 reveal the mechanism of chaperonin inactivation.
Not available
S-EPMC10053435 | biostudies-literature
UnknownHuman SCARB2 Acts as a Cellular Associator for Helping Coxsackieviruses A10 Infection.
Not available
S-EPMC10144829 | biostudies-literature
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