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GenomicsInactivation of the Budding Yeast Cohesin Loader Scc2 alters Gene Expression both Globally and in Response to a Single DNA Double Strand Break [ChIP-seq]
Genome integrity is fundamental for cell survival and cell cycle progression. Important mechanisms for keeping the genome intact are proper sister chromatid segregation, correct gene regulation and efficient repair of damaged DNA. Cohesin and its DNA loader, the Scc2/4 complex have been implicated i...
ORGANISM(S): Saccharomyces cerevisiae 
2014-10-21 | E-GEOD-62493 | biostudies-arrayexpress
TranscriptomicsInactivation of the Budding Yeast Cohesin Loader Scc2 alters Gene Expression both Globally and in Response to a Single DNA Double Strand Break
Genome integrity is fundamental for cell survival and cell cycle progression. Important mechanisms for keeping the genome intact are proper sister chromatid segregation, correct gene regulation and efficient repair of damaged DNA. Cohesin and its DNA loader, the Scc2/4 complex have been implicated i...
ORGANISM(S): Saccharomyces cerevisiae 
2014-10-16 | E-GEOD-61530 | biostudies-arrayexpress
TranscriptomicsThe age and genomic integrity of neurons after cortical stroke in humans
It has been unclear whether ischemic stroke induces neurogenesis or neuronal DNA-rearrangements in the human neocortex. We show here that neither is the case, using immunohistochemistry, transcriptome-, genome- and ploidy-analyses, and determination of nuclear bomb test-derived 14C-concentration in ...
ORGANISM(S): Homo sapiens 
2014-03-28 | E-GEOD-56267 | biostudies-arrayexpress
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